MULTISPECIES: LacI family DNA-binding transcriptional regulator

LOCUS       WP_002921918             338 aa            linear   BCT 20-NOV-2023
            [Klebsiella].
ACCESSION   WP_002921918
VERSION     WP_002921918.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 11265720
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..338
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     Protein         1..338
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /calculated_mol_wt=36957
     Region          7..77
                     /region_name="HTH_LACI"
                     /note="helix_turn _helix lactose operon repressor;
                     smart00354"
                     /db_xref="CDD:197675"
     Site            order(18..22,24..25,28,34..35,38,51,54,57..58,60..61)
                     /site_type="DNA binding"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:143331"
     Site            51..60
                     /site_type="active"
                     /note="domain linker motif [active]"
                     /db_xref="CDD:143331"
     Region          67..333
                     /region_name="PBP1_RegR_EndR_KdgR-like"
                     /note="ligand-binding domain of DNA transcription
                     repressor RegR and other putative regulators such as KdgR
                     and EndR; cd06283"
                     /db_xref="CDD:380506"
     Site            order(67,74,81..82,84..85,88,97..102,113,116,120,258,
                     261..262,265)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:380506"
     Site            order(79..80,83,128,151,164,201,224,280,297)
                     /site_type="other"
                     /note="putative ligand binding site [chemical binding]"
                     /db_xref="CDD:380506"
ORIGIN      
        1 makaaratis dvakaaktgk tsisrylnge khllsddlls riekaiaeld yrpslmargl
       61 khgrtrligl iiaditnpys vnvmsgieaa crekgftllv cntnneldqe lhyldllrsy
      121 qvegivvnav gmredglnrl qqsalpmvli drkipdfacd vvgldnaqaa ttatehlvek
      181 gfeailflse plgsvntrre rlsafratla rhhgvvaena evqlndgaml dnvlrqfhar
      241 hrgmrkavis angaltlqva ralkrvgliw gsdigllgfd elewaelagv gittlkqptw
      301 qigyaaveqv irriagtndp irervfsgel ivrgstsr