MULTISPECIES: aspartate 1-decarboxylase autocleavage activator PanM

LOCUS       WP_002920810             127 aa            linear   BCT 20-NOV-2023
            [Klebsiella].
ACCESSION   WP_002920810
VERSION     WP_002920810.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 127)
  AUTHORS   Monteiro,D.C.F., Patel,V., Bartlett,C.P., Nozaki,S., Grant,T.D.,
            Gowdy,J.A., Thompson,G.S., Kalverda,A.P., Snell,E.H., Niki,H.,
            Pearson,A.R. and Webb,M.E.
  TITLE     The structure of the PanD/PanZ protein complex reveals negative
            feedback regulation of pantothenate biosynthesis by coenzyme A
  JOURNAL   Chem. Biol. 22 (4), 492-503 (2015)
   PUBMED   25910242
REFERENCE   2  (residues 1 to 127)
  AUTHORS   Monteiro,D.C., Rugen,M.D., Shepherd,D., Nozaki,S., Niki,H. and
            Webb,M.E.
  TITLE     Formation of a heterooctameric complex between aspartate
            alpha-decarboxylase and its cognate activating factor, PanZ, is
            CoA-dependent
  JOURNAL   Biochem. Biophys. Res. Commun. 426 (3), 350-355 (2012)
   PUBMED   22940551
REFERENCE   3  (residues 1 to 127)
  AUTHORS   Stuecker,T.N., Tucker,A.C. and Escalante-Semerena,J.C.
  TITLE     PanM, an acetyl-coenzyme A sensor required for maturation of
            L-aspartate decarboxylase (PanD)
  JOURNAL   MBio 3 (4) (2012)
   PUBMED   22782525
REFERENCE   4  (residues 1 to 127)
  AUTHORS   Stuecker,T.N., Hodge,K.M. and Escalante-Semerena,J.C.
  TITLE     The missing link in coenzyme A biosynthesis: PanM (formerly YhhK),
            a yeast GCN5 acetyltransferase homologue triggers aspartate
            decarboxylase (PanD) maturation in Salmonella enterica
  JOURNAL   Mol. Microbiol. 84 (4), 608-619 (2012)
   PUBMED   22497218
  REMARK    Erratum:[Mol Microbiol. 2012 Aug;85(3):594-5]
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF033213.1
            Evidence Source    :: NCBIFAM
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..127
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     gene            1..127
                     /gene="panM"
     Protein         1..127
                     /product="aspartate 1-decarboxylase autocleavage activator
                     PanM"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0015940 - pantothenate biosynthetic
                     process [Evidence IEA]"
                     /GO_process="GO:0031638 - zymogen activation [Evidence
                     IEA]"
                     /calculated_mol_wt=14430
     Region          1..126
                     /region_name="matur_PanM"
                     /note="aspartate 1-decarboxylase autocleavage activator
                     PanM; NF033213"
                     /db_xref="CDD:411104"
ORIGIN      
        1 mkltiirlqh fsdqdridlg kiwpsqdlst ltldenhrly aarfnerllg avrvtlrgve
       61 gelsdlcvre vtrrrgvgqy lveetlrdnp ainswrvadh gvedrgvmaa fmqalgfsaq
      121 qngwekh