Unfortunately due to lack of commercial feasibility, the SkyBLAST service has been suspended from December 1st, 2025.
All subscriptions for paid accounts have been paused. For further information or enquiries, please email [email protected]

MULTISPECIES: Obg family GTPase CgtA [Enterobacteriaceae].


LOCUS       WP_002918377             392 aa            linear   BCT 08-FEB-2025
ACCESSION   WP_002918377
VERSION     WP_002918377.1
KEYWORDS    RefSeq.
SOURCE      Enterobacteriaceae
  ORGANISM  Enterobacteriaceae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales.
REFERENCE   1  (residues 1 to 392)
  AUTHORS   Shah,S., Das,B. and Bhadra,R.K.
  TITLE     Functional analysis of the essential GTP-binding-protein-coding
            gene cgtA of Vibrio cholerae
  JOURNAL   J Bacteriol 190 (13), 4764-4771 (2008)
   PUBMED   18456812
REFERENCE   2  (residues 1 to 392)
  AUTHORS   Raskin,D.M., Judson,N. and Mekalanos,J.J.
  TITLE     Regulation of the stringent response is the essential function of
            the conserved bacterial G protein CgtA in Vibrio cholerae
  JOURNAL   Proc Natl Acad Sci U S A 104 (11), 4636-4641 (2007)
   PUBMED   17360576
REFERENCE   3  (residues 1 to 392)
  AUTHORS   Jiang,M., Datta,K., Walker,A., Strahler,J., Bagamasbad,P.,
            Andrews,P.C. and Maddock,J.R.
  TITLE     The Escherichia coli GTPase CgtAE is involved in late steps of
            large ribosome assembly
  JOURNAL   J Bacteriol 188 (19), 6757-6770 (2006)
   PUBMED   16980477
REFERENCE   4  (residues 1 to 392)
  AUTHORS   Sato,A., Kobayashi,G., Hayashi,H., Yoshida,H., Wada,A., Maeda,M.,
            Hiraga,S., Takeyasu,K. and Wada,C.
  TITLE     The GTP binding protein Obg homolog ObgE is involved in ribosome
            maturation
  JOURNAL   Genes Cells 10 (5), 393-408 (2005)
   PUBMED   15836769
REFERENCE   5  (residues 1 to 392)
  AUTHORS   Datta,K., Skidmore,J.M., Pu,K. and Maddock,J.R.
  TITLE     The Caulobacter crescentus GTPase CgtAC is required for progression
            through the cell cycle and for maintaining 50S ribosomal subunit
            levels
  JOURNAL   Mol Microbiol 54 (5), 1379-1392 (2004)
   PUBMED   15554976
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR02729.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..392
                     /organism="Enterobacteriaceae"
                     /db_xref="taxon:543"
     gene            1..392
                     /gene="cgtA"
     Protein         1..392
                     /product="Obg family GTPase CgtA"
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0003924 - GTPase activity [Evidence IEA]"
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /calculated_mol_wt=43446
     Region          1..392
                     /region_name="obgE"
                     /note="GTPase CgtA; Reviewed; PRK12298"
                     /db_xref="CDD:237047"
ORIGIN      
        1 mkfvdeatil vvagdggngc vsfrrekyip kggpdggdgg dggdvwlead enlntlidyr
       61 feksfraerg qngqsrdctg krgkdvtvkv pvgtrvidqg tgetmgdmtk hgqrlmvakg
      121 gwhglgntrf kssvnrtprq ktmgtpgdkr dlqlelmlla dvgmlgmpna gkstfiravs
      181 aakpkvadyp fttlvpslgv vrmdneksfv vadipglieg aaegaglgir flkhlercrv
      241 llhlididpi dgsdpvenar iiigelekys eklaskprwl vfnkidlmdk aeaeakakai
      301 aealgweekf ylisaasqqg vkelcwdvmt fiienpivqa eeeqkpekve fmwddyhrqq
      361 leeaeaeaed dedwdddwde ddeegvefiy kr