Unfortunately due to lack of commercial feasibility, the SkyBLAST service has been suspended from December 1st, 2025.
All subscriptions for paid accounts have been paused. For further information or enquiries, please email [email protected]

MULTISPECIES: ATP-dependent zinc metalloprotease FtsH [Klebsiella].


LOCUS       WP_002918372             644 aa            linear   BCT 20-NOV-2023
ACCESSION   WP_002918372
VERSION     WP_002918372.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 644)
  AUTHORS   Krzywda,S., Brzozowski,A.M., Verma,C., Karata,K., Ogura,T. and
            Wilkinson,A.J.
  TITLE     The crystal structure of the AAA domain of the ATP-dependent
            protease FtsH of Escherichia coli at 1.5 A resolution
  JOURNAL   Structure 10 (8), 1073-1083 (2002)
   PUBMED   12176385
REFERENCE   2  (residues 1 to 644)
  AUTHORS   Krzywda,S., Brzozowski,A.M., Karata,K., Ogura,T. and Wilkinson,A.J.
  TITLE     Crystallization of the AAA domain of the ATP-dependent protease
            FtsH of Escherichia coli
  JOURNAL   Acta Crystallogr. D Biol. Crystallogr. 58 (Pt 6 Pt 2), 1066-1067
            (2002)
   PUBMED   12037319
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF008004.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK10733
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..644
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     gene            1..644
                     /gene="ftsH"
     Protein         1..644
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /EC_number="3.4.24.-"
                     /GO_function="GO:0004176 - ATP-dependent peptidase
                     activity [Evidence IEA]"
                     /GO_function="GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /calculated_mol_wt=70650
     Region          1..644
                     /region_name="hflB"
                     /note="ATP-dependent zinc metalloprotease FtsH; PRK10733"
                     /db_xref="CDD:182683"
ORIGIN      
        1 maknlilwlv iavvlmsvfq sfgpsesngr kvdystflqe vnqdqvrear ingreinvtk
       61 kdsnryttyi pvndpklldn lltknvkvvg eppeepslla sifiswfpml lligvwiffm
      121 rqmqggggkg amsfgkskar mltedqiktt fadvagcdea keevgelvey lrepsrfqkl
      181 ggkipkgvlm vgppgtgktl lakaiageak vpfftisgsd fvemfvgvga srvrdmfeqa
      241 kkaapciifi deidavgrqr gaglggghde reqtlnqmlv emdgfegneg iiviaatnrp
      301 dvldpallrp grfdrqvvvg lpdvrgreqi lkvhmrrvpl apdidaaiia rgtpgfsgad
      361 lanlvneaal faargnkrvv smvefekakd kimmgaerrs mvmteaqkes tayheaghai
      421 igrlvpehdp vhkvtiiprg ralgvtfflp egdaisasrq klesqistly ggrlaeeiiy
      481 gpehvstgas ndikvatnla rnmvtqwgfs dklgpllyae eegevflgrs vakakhmsde
      541 tariidqevk sliernygra rqllndnmdi lhamkdalmk yetidapqid dlmarrevrp
      601 pagweepgss nnsdnngtpr aprpvdeprt pnpgntmseq lgdk