MULTISPECIES: dihydropteroate synthase [Enterobacteriaceae].

LOCUS       WP_002918371             282 aa            linear   BCT 15-SEP-2023
ACCESSION   WP_002918371
VERSION     WP_002918371.1
KEYWORDS    RefSeq.
SOURCE      Enterobacteriaceae
  ORGANISM  Enterobacteriaceae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF008625.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK11613
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..282
                     /organism="Enterobacteriaceae"
                     /db_xref="taxon:543"
     gene            1..282
                     /gene="folP"
     Protein         1..282
                     /product="dihydropteroate synthase"
                     /EC_number="2.5.1.15"
                     /GO_function="GO:0004156 - dihydropteroate synthase
                     activity [Evidence IEA]"
                     /calculated_mol_wt=30296
     Region          1..282
                     /region_name="folP"
                     /note="dihydropteroate synthase; Provisional; PRK11613"
                     /db_xref="CDD:183230"
     Site            order(22,96,115,117,139,185,217,221,255,257)
                     /site_type="other"
                     /note="substrate binding pocket [chemical binding]"
                     /db_xref="CDD:238380"
     Site            order(198,202..203,241,245,249,264..265)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:238380"
     Site            219..221
                     /site_type="active"
                     /note="inhibitor binding site [active]"
                     /db_xref="CDD:238380"
ORIGIN      
        1 mklvaqgstl dlshphvmgi lnvtpdsfsd ggahnsliea vkhanlmina gatiidigge
       61 strpgaaevs veeelarvip vveaiaqrfe vwisvdtska evirqsarag ahiindirsl
      121 tepgalqaaa etglpvclmh mqgqpktmqe apkyedvfad verffnehiv rceqagiake
      181 kllldpgfgf gknlshnyql larlgefhhf glpllvgmsr ksmvgqllnv gpserlngsl
      241 acaviaamqg aqiirvhdvk etvealrvve atlaakgkkr ye