MULTISPECIES: translation initiation factor IF-2 [Klebsiella].

LOCUS       WP_002918250             896 aa            linear   BCT 03-JUN-2024
ACCESSION   WP_002918250
VERSION     WP_002918250.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 896)
  AUTHORS   Roy,B., Liu,Q., Shoji,S. and Fredrick,K.
  TITLE     IF2 and unique features of initiator tRNAfMet help establish the
            translational reading frame
  JOURNAL   RNA Biol 15 (4-5), 604-613 (2018)
   PUBMED   28914580
REFERENCE   2  (residues 1 to 896)
  AUTHORS   Sacerdot,C., Vachon,G., Laalami,S., Morel-Deville,F., Cenatiempo,Y.
            and Grunberg-Manago,M.
  TITLE     Both forms of translational initiation factor IF2 (alpha and beta)
            are required for maximal growth of Escherichia coli. Evidence for
            two translational initiation codons for IF2 beta
  JOURNAL   J Mol Biol 225 (1), 67-80 (1992)
   PUBMED   1374802
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR00487.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..896
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     gene            1..896
                     /gene="infB"
     Protein         1..896
                     /product="translation initiation factor IF-2"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0003743 - translation initiation factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0003924 - GTPase activity [Evidence IEA]"
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /GO_process="GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /calculated_mol_wt=97945
     Region          1..52
                     /region_name="IF2_N"
                     /note="Translation initiation factor IF-2, N-terminal
                     region; pfam04760"
                     /db_xref="CDD:428110"
     Region          57..95
                     /region_name="IF2_assoc"
                     /note="Bacterial translation initiation factor IF-2
                     associated region; pfam08364"
                     /db_xref="CDD:429947"
     Region          <131..316
                     /region_name="PTZ00121"
                     /note="MAEBL; Provisional"
                     /db_xref="CDD:173412"
     Region          320..370
                     /region_name="IF2_N"
                     /note="Translation initiation factor IF-2, N-terminal
                     region; pfam04760"
                     /db_xref="CDD:428110"
     Region          394..895
                     /region_name="InfB"
                     /note="Translation initiation factor IF-2, a GTPase
                     [Translation, ribosomal structure and biogenesis];
                     COG0532"
                     /db_xref="CDD:440298"
ORIGIN      
        1 mtdvtikala seiqtsvdrl iqqfadagir ksaddsvtsq ekqtllthln rehgsapdkl
       61 tlqrktrstl nipgtggksk svqievrkkr tfvkrdpqea erlaaeeqaq reaeeqarre
      121 aeeaakreaq lkaereaaeq akrevadkak reaaekdkvs nqhtdemtkt aqaekirren
      181 eaaelkrkse eearrkleee arrvaeearr maeeneknws etsdspedss dyhvttsqha
      241 rqaeddndre veggrgrsrs skaarpakkg nkhaeskadr eearaavrgg kggkhrkgsa
      301 lqqgfqkpaq avnrdvvige titvgelank mavkgsqvik ammklgamat inqvidqeta
      361 qlvaeemghk vilrrenele eavmsdrdtg aaaeprapvv timghvdhgk tslldyirst
      421 kvasgeaggi tqhigayhve tdngmitfld tpghaaftsm rargaqatdi vvlvvaaddg
      481 vmpqtieaiq hakaaqvpvv vavnkidkpe adpdrvknel sqygilpeew ggesqfvhvs
      541 akagtgiddl ldaillqaev lelkavrngm asgaviesfl dkgrgpvatv lvregtlhkg
      601 divlcgfeyg rvramrdelg revleagpsi pveilglsgv paagdevtvv rdekkareva
      661 lyrqgkfrev klarqqkskl enmfanmteg evhevnivlk advqgsveai sdsllklstd
      721 evkvkiigsg vggitetdat laaasnailv gfnvradasa rkvieaesld lryysviynl
      781 idevkaamsg mlspelkqqi iglaevrdvf kspkfgaiag cmvtegtikr hnpirvlrdn
      841 vviyegeles lrrfkddvne vrngmecgig vknyndvrvg dmievfeiie iqrsid