MULTISPECIES: tagatose bisphosphate family class II aldolase

LOCUS       WP_002917968             284 aa            linear   BCT 03-JUN-2024
            [Klebsiella].
ACCESSION   WP_002917968
VERSION     WP_002917968.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 284)
  AUTHORS   Hall,D.R., Bond,C.S., Leonard,G.A., Watt,C.I., Berry,A. and
            Hunter,W.N.
  TITLE     Structure of tagatose-1,6-bisphosphate aldolase. Insight into
            chiral discrimination, mechanism, and specificity of class II
            aldolases
  JOURNAL   J Biol Chem 277 (24), 22018-22024 (2002)
   PUBMED   11940603
REFERENCE   2  (residues 1 to 284)
  AUTHORS   Zgiby,S.M., Thomson,G.J., Qamar,S. and Berry,A.
  TITLE     Exploring substrate binding and discrimination in fructose1,
            6-bisphosphate and tagatose 1,6-bisphosphate aldolases
  JOURNAL   Eur J Biochem 267 (6), 1858-1868 (2000)
   PUBMED   10712619
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR01858.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..284
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     Protein         1..284
                     /product="tagatose bisphosphate family class II aldolase"
                     /EC_number="4.1.2.40"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0009025 - tagatose-bisphosphate aldolase
                     activity [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /calculated_mol_wt=30692
     Region          1..284
                     /region_name="gatY"
                     /note="tagatose-bisphosphate aldolase subunit GatY;
                     PRK12737"
                     /db_xref="CDD:183710"
     Site            order(27..29,32,52,55..57,61,65,68..69,142,233..234,
                     236..237,240,244,247)
                     /site_type="other"
                     /note="intersubunit interface [polypeptide binding]"
                     /db_xref="CDD:238477"
     Site            order(82..83,179..181,183,208..209,211,230,232..233)
                     /site_type="active"
                     /db_xref="CDD:238477"
     Site            order(83,180,208)
                     /site_type="other"
                     /note="zinc binding site [ion binding]"
                     /db_xref="CDD:238477"
     Site            order(179,181,183,209,211)
                     /site_type="other"
                     /note="Na+ binding site [ion binding]"
                     /db_xref="CDD:238477"
ORIGIN      
        1 myiissknml lkaqrqsyav pafnihnlet mqvvvetaae lrsplilagt pgtysyagtg
       61 nvvaiardla kkwdlplalh ldhhedladi trkvqagirs vmidgshspf eenvalvksv
      121 velshrydas veaelgrlgg veddlvvdak dalytnpeqa refvartgid slavaigtah
      181 glytaepkld ferlaairdc vdvplvlhga sglpdsdirr aislgvckvn vatelkiafs
      241 dalkayflen pgandprhym kpakaamkev vrkvihvcgc egql