Unfortunately due to lack of commercial feasibility, the SkyBLAST service has been suspended from December 1st, 2025.
All subscriptions for paid accounts have been paused. For further information or enquiries, please email [email protected]

MULTISPECIES: 3-hydroxy-5-phosphonooxypentane-2,4-dione thiolase


LOCUS       WP_002917724             295 aa            linear   BCT 20-NOV-2023
            [Klebsiella].
ACCESSION   WP_002917724
VERSION     WP_002917724.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF006081.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK08227
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..295
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     gene            1..295
                     /gene="lsrF"
     Protein         1..295
                     /product="3-hydroxy-5-phosphonooxypentane-2,4-dione
                     thiolase"
                     /EC_number="2.3.1.245"
                     /GO_function="GO:0016829 - lyase activity [Evidence IEA]"
                     /calculated_mol_wt=32280
     Region          28..291
                     /region_name="PRK08227"
                     /note="3-hydroxy-5-phosphonooxypentane-2,4-dione thiolase"
                     /db_xref="CDD:181306"
     Site            order(217,220,241..243,263..265)
                     /site_type="other"
                     /note="putative active site"
                     /db_xref="CDD:188645"
     Site            217
                     /site_type="active"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:188645"
ORIGIN      
        1 madlddikeg kdfgidrpqq ntlytlkgcg sldwgmqsrl arifnphsnr tvmlafdhgy
       61 fqgpttgler idlsiaplfa dtdvlmctrg vlrsqvpaat nkpvvlrasg gnsilselsn
      121 ecvavameda lrlnvcavaa qvyigseyeh qsinniiklv dagnrygmpv lavtgvgkem
      181 trdaryfsla sriaaemgaq fvktyfveeg fekvtascpv piviaggkkl pehealemcw
      241 raidqgasgv dmgrnifqss apramlkavk kvvhenlnar eayqfwqeek qgelk