MULTISPECIES: urease accessory protein UreD [Klebsiella].

LOCUS       WP_002916869             274 aa            linear   BCT 02-MAR-2025
ACCESSION   WP_002916869
VERSION     WP_002916869.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 274)
  AUTHORS   Farrugia,M.A., Wang,B., Feig,M. and Hausinger,R.P.
  TITLE     Mutational and Computational Evidence That a Nickel-Transfer Tunnel
            in UreD Is Used for Activation of Klebsiella aerogenes Urease
  JOURNAL   Biochemistry 54 (41), 6392-6401 (2015)
   PUBMED   26401965
REFERENCE   2  (residues 1 to 274)
  AUTHORS   Farrugia,M.A., Macomber,L. and Hausinger,R.P.
  TITLE     Biosynthesis of the urease metallocenter
  JOURNAL   J Biol Chem 288 (19), 13178-13185 (2013)
   PUBMED   23539618
REFERENCE   3  (residues 1 to 274)
  AUTHORS   Moncrief,M.B. and Hausinger,R.P.
  TITLE     Characterization of UreG, identification of a UreD-UreF-UreG
            complex, and evidence suggesting that a nucleotide-binding site in
            UreG is required for in vivo metallocenter assembly of Klebsiella
            aerogenes urease
  JOURNAL   J Bacteriol 179 (13), 4081-4086 (1997)
   PUBMED   9209019
REFERENCE   4  (residues 1 to 274)
  AUTHORS   Neyrolles,O., Ferris,S., Behbahani,N., Montagnier,L. and
            Blanchard,A.
  TITLE     Organization of Ureaplasma urealyticum urease gene cluster and
            expression in a suppressor strain of Escherichia coli
  JOURNAL   J Bacteriol 178 (3), 647-655 (1996)
   PUBMED   8550495
  REMARK    Erratum:[J Bacteriol. 1996 May;178(9):2725. doi:
            10.1128/jb.178.9.2725-2725.1996.. PMID: 8626347]
REFERENCE   5  (residues 1 to 274)
  AUTHORS   Park,I.S., Carr,M.B. and Hausinger,R.P.
  TITLE     In vitro activation of urease apoprotein and role of UreD as a
            chaperone required for nickel metallocenter assembly
  JOURNAL   Proc Natl Acad Sci U S A 91 (8), 3233-3237 (1994)
   PUBMED   7909161
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10002853
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..274
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     Protein         1..274
                     /product="urease accessory protein UreD"
                     /GO_function="GO:0016151 - nickel cation binding [Evidence
                     IEA]"
                     /GO_process="GO:0008152 - metabolic process [Evidence
                     IEA]"
                     /calculated_mol_wt=30081
     Region          2..274
                     /region_name="UreH"
                     /note="Urease accessory protein UreH [Posttranslational
                     modification, protein turnover, chaperones]; COG0829"
                     /db_xref="CDD:440591"
ORIGIN      
        1 mhgtvlpplk kgwqatldlr fhqaggktvl asaqhvgplt vqrpfypeee tchlyllhpp
       61 ggivggdelt isahlapgch tlitmpgask fyrssgaqal vrqqltlapq atlewlpqda
      121 iffpganarl fttfhlcass rllawdllcl grpvigetfs hgtlsnrlev wvddepllve
      181 rlqlqegels svaerpwvgt llcypatdal ldgvrdalap lglyagaslt drlltvrfls
      241 ddnlicqrvm rdvwqflrph ltgkspvlpr iwlt