Unfortunately due to lack of commercial feasibility, the SkyBLAST service has been suspended from December 1st, 2025.
All subscriptions for paid accounts have been paused. For further information or enquiries, please email [email protected]

MULTISPECIES: quorum sensing histidine kinase QseC [Klebsiella].


LOCUS       WP_002916838             449 aa            linear   BCT 09-FEB-2023
ACCESSION   WP_002916838
VERSION     WP_002916838.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 449)
  AUTHORS   Lv,J., Zhu,J., Wang,T., Xie,X., Wang,T., Zhu,Z., Chen,L., Zhong,F.
            and Du,H.
  TITLE     The Role of the Two-Component QseBC Signaling System in Biofilm
            Formation and Virulence of Hypervirulent Klebsiella pneumoniae
            ATCC43816
  JOURNAL   Front Microbiol 13, 817494 (2022)
   PUBMED   35464966
  REMARK    Publication Status: Online-Only
REFERENCE   2  (residues 1 to 449)
  AUTHORS   Breland,E.J., Zhang,E.W., Bermudez,T., Martinez,C.R. 3rd and
            Hadjifrangiskou,M.
  TITLE     The Histidine Residue of QseC Is Required for Canonical Signaling
            between QseB and PmrB in Uropathogenic Escherichia coli
  JOURNAL   J Bacteriol 199 (18), e00060-17 (2017)
   PUBMED   28396353
  REMARK    Publication Status: Online-Only
REFERENCE   3  (residues 1 to 449)
  AUTHORS   Weigel,W.A. and Demuth,D.R.
  TITLE     QseBC, a two-component bacterial adrenergic receptor and global
            regulator of virulence in Enterobacteriaceae and Pasteurellaceae
  JOURNAL   Mol Oral Microbiol 31 (5), 379-397 (2016)
   PUBMED   26426681
REFERENCE   4  (residues 1 to 449)
  AUTHORS   Sperandio,V., Torres,A.G. and Kaper,J.B.
  TITLE     Quorum sensing Escherichia coli regulators B and C (QseBC): a novel
            two-component regulatory system involved in the regulation of
            flagella and motility by quorum sensing in E. coli
  JOURNAL   Mol Microbiol 43 (3), 809-821 (2002)
   PUBMED   11929534
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF007664.1
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK10337
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     gene            1..449
                     /gene="qseC"
     Protein         1..449
                     /product="quorum sensing histidine kinase QseC"
                     /EC_number="2.7.13.3"
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /calculated_mol_wt=50706
     Region          17..449
                     /region_name="PRK10337"
                     /note="sensor protein QseC; Provisional"
                     /db_xref="CDD:182388"
ORIGIN      
        1 mkrlarlslr lrltllfavl ttaawgmasv iawqqtskkl dklfdtqqll farrlsvmhf
       61 delrappall gekkkvrhgh idddalafai ftrdgkmvln dgengediqw nsqregfsdg
      121 ylrddddewr flwlttadgr yriavgqewd yrremamdiv tsqltpwmva lplmfvlliv
      181 llsrelaplk nlartlrlra pdsadslsve kipaevrplv ealnqlfrrt hdamlrerrf
      241 tsdaahelrs plaalkvqte vaqlslddpe grekaldqlh qgidratrlv dqlltlsrld
      301 slaqlddvqq vaiadllqsa vmemyhpaqq sgielrlhln ashivrtgqp lllsllvrnl
      361 ldnavryspc gsqvditlna refrvrdngp ginpqalsri gerfyrppgq eapgsglgls
      421 ivrriaslhg mqvdfanard ggfearvyw