MULTISPECIES: sugar porter family MFS transporter [Klebsiella].

LOCUS       WP_002916587             464 aa            linear   BCT 07-NOV-2024
ACCESSION   WP_002916587
VERSION     WP_002916587.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 464)
  AUTHORS   Custodio,T.F., Paulsen,P.A., Frain,K.M. and Pedersen,B.P.
  TITLE     Structural comparison of GLUT1 to GLUT3 reveal transport regulation
            mechanism in sugar porter family
  JOURNAL   Life Sci Alliance 4 (4), e202000858 (2021)
   PUBMED   33536238
  REMARK    Publication Status: Online-Only
REFERENCE   2  (residues 1 to 464)
  AUTHORS   Quistgaard,E.M., Low,C., Guettou,F. and Nordlund,P.
  TITLE     Understanding transport by the major facilitator superfamily (MFS):
            structures pave the way
  JOURNAL   Nat Rev Mol Cell Biol 17 (2), 123-132 (2016)
   PUBMED   26758938
REFERENCE   3  (residues 1 to 464)
  AUTHORS   Yan,N.
  TITLE     Structural Biology of the Major Facilitator Superfamily
            Transporters
  JOURNAL   Annu Rev Biophys 44, 257-283 (2015)
   PUBMED   26098515
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 11489872
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     Protein         1..464
                     /product="sugar porter family MFS transporter"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport
                     [Evidence IEA]"
                     /calculated_mol_wt=50738
     Region          9..447
                     /region_name="SP"
                     /note="MFS transporter, sugar porter (SP) family;
                     TIGR00879"
                     /db_xref="CDD:273317"
     Site            order(29,33,147,150..151,154,262..263,267..268,271..272,
                     300,362..363,366..367,371,394..395,398)
                     /site_type="other"
                     /note="chemical substrate binding pocket [chemical
                     binding]"
                     /db_xref="CDD:340873"
ORIGIN      
        1 mpdnkkqgrs nktmtffvcf laalagllfg ldigviagal pfianefqis ahtqewvvss
       61 mmfgaavgav gsgwlsfklg rkkslmigai lfvagslfsa aapnveillv srvllglavg
      121 vasytaplyl seiapekirg smismyqlmi tigilgayls dtafsysgaw rwmlgviiip
      181 avllligvif lpdsprwfaa krrfvdaerv llrlrdtsae akreldeire slkvkqsgws
      241 lfkdnsnfrr avflgillqv mqqftgmnvi myyapkifel agyantteqm wgtvivgltn
      301 vlatfiaigl vdrwgrkptl ilgfivmaag mgvlgtmmhi gihsstaqyi avlmllmfiv
      361 gfamsagpli wvlcseiqpl kgrdfgitcs tatnwianmi vgatfltmln slgsantfwv
      421 ygglnvlfil ltlwlipetk nvslehiern lmqgrplrei gard