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MULTISPECIES: LysR family transcriptional regulator [Klebsiella].


LOCUS       WP_002916293             309 aa            linear   BCT 01-JAN-2025
ACCESSION   WP_002916293
VERSION     WP_002916293.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 309)
  AUTHORS   Maddocks,S.E. and Oyston,P.C.F.
  TITLE     Structure and function of the LysR-type transcriptional regulator
            (LTTR) family proteins
  JOURNAL   Microbiology (Reading) 154 (Pt 12), 3609-3623 (2008)
   PUBMED   19047729
REFERENCE   2  (residues 1 to 309)
  AUTHORS   Schell,M.A.
  TITLE     Molecular biology of the LysR family of transcriptional regulators
  JOURNAL   Annu Rev Microbiol 47, 597-626 (1993)
   PUBMED   8257110
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10444099
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..309
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     Protein         1..309
                     /product="LysR family transcriptional regulator"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription
                     factor activity [Evidence IEA]"
                     /calculated_mol_wt=33753
     Region          6..62
                     /region_name="HTH_1"
                     /note="Bacterial regulatory helix-turn-helix protein, lysR
                     family; pfam00126"
                     /db_xref="CDD:459683"
     Region          98..297
                     /region_name="PBP2_DntR_like_1"
                     /note="The C-terminal substrate binding domain of an
                     uncharacterized LysR-type transcriptional regulator
                     similar to DntR, which is involved in the catabolism of
                     dinitrotoluene; contains the type 2 periplasmic binding
                     fold; cd08460"
                     /db_xref="CDD:176149"
     Site            order(103,105..106,110,167,205,272)
                     /site_type="other"
                     /note="putative substrate binding pocket [chemical
                     binding]"
                     /db_xref="CDD:176149"
     Site            order(104,107..108,111..112,115..116,118..119,122..123,
                     125..129,131,194,222..226,229..230,233..234,237,251)
                     /site_type="other"
                     /note="putative dimerization interface [polypeptide
                     binding]"
                     /db_xref="CDD:176149"
ORIGIN      
        1 msdpdfnllv aldvllseas vagaarrlnl stsamsrtls rlrdvtgdpi lvragrnmvl
       61 tpwaeatrdr arravhdara vlqpstetfs aqnlarlfti randgfvvaf gpaliaavad
      121 aapdvcirfa pkpektsryl reglvdleig vqsnmgpeir lqrlfedrfv gvvrkghpla
      181 kqaeigvsdy vawghvvasp egalhgsvdd alaelgtkrk iasvvpgfpt alsvalesdl
      241 iamipalyll nqqvtdqvhl felpfksrri tvsqmwhprm erdpghrwlr eqilaicgva
      301 rsvmtkepv