MULTISPECIES: acetyl-CoA C-acetyltransferase [Klebsiella].

LOCUS       WP_002916052             392 aa            linear   BCT 31-DEC-2024
ACCESSION   WP_002916052
VERSION     WP_002916052.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 392)
  AUTHORS   Merilainen,G., Poikela,V., Kursula,P. and Wierenga,R.K.
  TITLE     The thiolase reaction mechanism: the importance of Asn316 and
            His348 for stabilizing the enolate intermediate of the Claisen
            condensation
  JOURNAL   Biochemistry 48 (46), 11011-11025 (2009)
   PUBMED   19842716
REFERENCE   2  (residues 1 to 392)
  AUTHORS   Igual,J.C., Gonzalez-Bosch,C., Dopazo,J. and Perez-Ortin,J.E.
  TITLE     Phylogenetic analysis of the thiolase family. Implications for the
            evolutionary origin of peroxisomes
  JOURNAL   J Mol Evol 35 (2), 147-155 (1992)
   PUBMED   1354266
REFERENCE   3  (residues 1 to 392)
  AUTHORS   LYNEN,F. and OCHOA,S.
  TITLE     Enzymes of fatty acid metabolism
  JOURNAL   Biochim Biophys Acta 12 (1-2), 299-314 (1953)
   PUBMED   13115439
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 11481662
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..392
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     Protein         1..392
                     /product="acetyl-CoA C-acetyltransferase"
                     /EC_number="2.3.1.9"
                     /GO_function="GO:0003985 - acetyl-CoA C-acetyltransferase
                     activity [Evidence IEA]"
                     /calculated_mol_wt=40948
     Region          1..391
                     /region_name="PRK05790"
                     /note="putative acyltransferase; Provisional"
                     /db_xref="CDD:180261"
ORIGIN      
        1 mkdvvivgal rtpigcfqga lsrhsavelg svvvkalvek tgidphsvde vilgqvltag
       61 tgqnparqsa irgglpntvs aitindvcgs glkalhlatq aiqcgeadvv iaggqenmsr
      121 aphvltdsrt gaqlgnsqli dslvhdglwd afndyhmgvt aenlarefgi srelqdawal
      181 ssqhkarkai dsgrfrdeiv pvvtehngaa rtvdtdeqpr vdasaeglas lqptfdrlgs
      241 vtagnassin dgaaavmmms eakalelglp ilarirafas vgvdpalmgi apvhatrrcl
      301 eragwrlddv dlieaneafa aqaisvgrvl ewderrvnvn ggaialghpi gasgcrilvs
      361 lvhemikrda rkglatlcig ggqgvalave ra