MULTISPECIES: diaminopimelate decarboxylase [Klebsiella].

LOCUS       WP_002915990             420 aa            linear   BCT 20-NOV-2023
ACCESSION   WP_002915990
VERSION     WP_002915990.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR01048.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     gene            1..420
                     /gene="lysA"
     Protein         1..420
                     /product="diaminopimelate decarboxylase"
                     /EC_number="4.1.1.20"
                     /GO_function="GO:0008836 - diaminopimelate decarboxylase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /calculated_mol_wt=45910
     Region          2..419
                     /region_name="PLPDE_III"
                     /note="Type III Pyridoxal 5-phosphate (PLP)-Dependent
                     Enzymes; cl00261"
                     /db_xref="CDD:469695"
     Site            order(52,54,73,100,142,189,191,194,226..227,268..271,307,
                     311,342,378,382,386)
                     /site_type="active"
                     /db_xref="CDD:143501"
     Site            order(52,54,73,100,142,189,191,194,226..227,268..271,342,
                     378)
                     /site_type="other"
                     /note="pyridoxal 5'-phosphate (PLP) binding site [chemical
                     binding]"
                     /db_xref="CDD:143501"
     Site            order(54,191,194,271,307,311,342..343,378,382,386)
                     /site_type="other"
                     /note="substrate binding site [chemical binding]"
                     /db_xref="CDD:143501"
     Site            order(54,342)
                     /site_type="active"
                     /note="catalytic residues [active]"
                     /db_xref="CDD:143501"
     Site            order(59..60,75..76,78..79,102..104,108,122,125,162..165,
                     286,288,295,297,339..344,346,381..383,385..388,391)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:143501"
ORIGIN      
        1 mphslyatdt dltadnllrl paefgcpvwv ydaqiirrqi aqlsqfdvvr faqkacsnih
       61 ilrlmreqgv kvdsvslgei eralaagydp qqnpedivft adliddatld rvkalqipvn
      121 agsidmlsql gevspghrvw lrvnpgfghg hsqktntgge nskhgiwysh lpaalevmrr
      181 yqlqlvgihm higsgvdygh leqvcgamvr qvvdfgqdlq aisaggglsi pyregeeaid
      241 tahyyglwnr areqiaahlg hpvkleiepg rflvaesgvl vsqvrsvkem gsrhfvlida
      301 gfndlmrpam ygsyhhital agdgrdlsaa pqvetvvagp lcesgdvftq qeggkvetrl
      361 lpavapgdyl vlhdtgayga smssnynsrp llpevlfdgg karlirrrqt iqellaleli