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MULTISPECIES: MetQ/NlpA family ABC transporter substrate-binding


LOCUS       WP_002915265             292 aa            linear   BCT 01-MAR-2025
            protein [Klebsiella].
ACCESSION   WP_002915265
VERSION     WP_002915265.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 292)
  AUTHORS   Nguyen,P.T., Lai,J.Y., Lee,A.T., Kaiser,J.T. and Rees,D.C.
  TITLE     Noncanonical role for the binding protein in substrate uptake by
            the MetNI methionine ATP Binding Cassette (ABC) transporter
  JOURNAL   Proc Natl Acad Sci U S A 115 (45), E10596-E10604 (2018)
   PUBMED   30352853
REFERENCE   2  (residues 1 to 292)
  AUTHORS   Schwechheimer,C. and Kuehn,M.J.
  TITLE     Synthetic effect between envelope stress and lack of outer membrane
            vesicle production in Escherichia coli
  JOURNAL   J Bacteriol 195 (18), 4161-4173 (2013)
   PUBMED   23852867
REFERENCE   3  (residues 1 to 292)
  AUTHORS   Zhang,Z., Feige,J.N., Chang,A.B., Anderson,I.J., Brodianski,V.M.,
            Vitreschak,A.G., Gelfand,M.S. and Saier,M.H. Jr.
  TITLE     A transporter of Escherichia coli specific for L- and D-methionine
            is the prototype for a new family within the ABC superfamily
  JOURNAL   Arch Microbiol 180 (2), 88-100 (2003)
   PUBMED   12819857
REFERENCE   4  (residues 1 to 292)
  AUTHORS   Gal,J., Szvetnik,A., Schnell,R. and Kalman,M.
  TITLE     The metD D-methionine transporter locus of Escherichia coli is an
            ABC transporter gene cluster
  JOURNAL   J Bacteriol 184 (17), 4930-4932 (2002)
   PUBMED   12169620
REFERENCE   5  (residues 1 to 292)
  AUTHORS   Yu,F., Inouye,S. and Inouye,M.
  TITLE     Lipoprotein-28, a cytoplasmic membrane lipoprotein from Escherichia
            coli. Cloning, DNA sequence, and expression of its gene
  JOURNAL   J Biol Chem 261 (5), 2284-2288 (1986)
   PUBMED   3003106
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF015159.6
            Evidence Source    :: EMBL-EBI
            Source Identifier  :: PF03180.19
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..292
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     Protein         1..292
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /calculated_mol_wt=32515
     Region          9..>41
                     /region_name="PRK11556"
                     /note="MdtA/MuxA family multidrug efflux RND transporter
                     periplasmic adaptor subunit"
                     /db_xref="CDD:183194"
     Region          47..276
                     /region_name="PBP2_lipoprotein_like_1"
                     /note="Putative periplasmic-binding component of ABC-type
                     methionine uptake transporter system-like; the type 2
                     periplasmic binding protein fold; cd13600"
                     /db_xref="CDD:270318"
     Site            order(86,103..105,108,158,161,218,220,244)
                     /site_type="other"
                     /note="putative chemical substrate binding site [chemical
                     binding]"
                     /db_xref="CDD:270318"
ORIGIN      
        1 mtteqfelrk arrwpwlaal aviillaiaf wwwrghtqsq qvvfgstlki hyepamageq
       61 riieyinqhi apdyglklea vgvqdpvqad ravaegqyag tiyqhqwwlk qvvdangfal
      121 sttvpvfqwa fgiysdryss vqalpngati vvpddganqg qalwllqrig lisldpavep
      181 rtaklknivg nphqfvfkel dlltmpraln svdaaigyvs qfdagkvpre kgilfppapr
      241 tfasqlvigt pylsqenivk lkqafsdpri qtwlkttddp lvkdvlvpvs ae