Unfortunately due to lack of commercial feasibility, the SkyBLAST service has been suspended from December 1st, 2025.
All subscriptions for paid accounts have been paused. For further information or enquiries, please email [email protected]

MULTISPECIES: L-serine ammonia-lyase [Klebsiella].


LOCUS       WP_002915259             455 aa            linear   BCT 04-JUN-2024
ACCESSION   WP_002915259
VERSION     WP_002915259.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 455)
  AUTHORS   Burman,J.D., Harris,R.L., Hauton,K.A., Lawson,D.M. and Sawers,R.G.
  TITLE     The iron-sulfur cluster in the L-serine dehydratase TdcG from
            Escherichia coli is required for enzyme activity
  JOURNAL   FEBS Lett 576 (3), 442-444 (2004)
   PUBMED   15498577
REFERENCE   2  (residues 1 to 455)
  AUTHORS   Su,H., Moniakis,J. and Newman,E.B.
  TITLE     Use of gene fusions of the structural gene sdaA to purify L-serine
            deaminase 1 from Escherichia coli K-12
  JOURNAL   Eur J Biochem 211 (3), 521-527 (1993)
   PUBMED   8436113
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR00720.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..455
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     Protein         1..455
                     /product="L-serine ammonia-lyase"
                     /EC_number="4.3.1.17"
                     /GO_function="GO:0003941 - L-serine ammonia-lyase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006094 - gluconeogenesis [Evidence IEA]"
                     /calculated_mol_wt=48356
     Region          2..451
                     /region_name="sda_mono"
                     /note="L-serine dehydratase, iron-sulfur-dependent, single
                     chain form; TIGR00720"
                     /db_xref="CDD:273233"
ORIGIN      
        1 misvfdifki gigpssshtv gpmkagkqft ddliarglla evskvvvdvy gslsltgkgh
       61 htdiaiimgl agnlpdtvdi daipgfiqdv nthgrlmlan gqhevdfpvd qcmnfhadnl
      121 slhengmrit alagdkvlys qtyysigggf ivdeehfgqt teapvavpyp yknaadlqrh
      181 cretglslsg lmmqnelalh skealeqhfa avwevmsagi ergittegvl pgklrvprra
      241 aalrrmlvsq dttnsdpmav vdwinmfala vneenaaggr vvtaptngac givpavlayy
      301 dkfirkvnsn slarymlvas aigslykmna sisgaevgcq gevgvacsma aaglaellgg
      361 spgqvciaae iamehnlglt cdpvagqvqv pciernaiaa vkavnaarma lrrtseprvc
      421 ldkvietmye tgkdmnakyr etsrgglamk ivacd