MULTISPECIES: glucarate dehydratase [Klebsiella].

LOCUS       WP_002915223             446 aa            linear   BCT 08-JUL-2020
ACCESSION   WP_002915223
VERSION     WP_002915223.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 446)
  AUTHORS   Gulick,A.M., Hubbard,B.K., Gerlt,J.A. and Rayment,I.
  TITLE     Evolution of enzymatic activities in the enolase superfamily:
            identification of the general acid catalyst in the active site of
            D-glucarate dehydratase from Escherichia coli
  JOURNAL   Biochemistry 40 (34), 10054-10062 (2001)
   PUBMED   11513584
REFERENCE   2  (residues 1 to 446)
  AUTHORS   Hubbard,B.K., Koch,M., Palmer,D.R., Babbitt,P.C. and Gerlt,J.A.
  TITLE     Evolution of enzymatic activities in the enolase superfamily:
            characterization of the (D)-glucarate/galactarate catabolic pathway
            in Escherichia coli
  JOURNAL   Biochemistry 37 (41), 14369-14375 (1998)
   PUBMED   9772162
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR03247.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     gene            1..446
                     /gene="gudD"
     Protein         1..446
                     /product="glucarate dehydratase"
                     /EC_number="4.2.1.40"
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0008872 - glucarate dehydratase activity
                     [Evidence IEA]"
                     /GO_process="GO:0019394 - glucarate catabolic process
                     [Evidence IEA]"
                     /calculated_mol_wt=48863
     Region          5..446
                     /region_name="glucar-dehydr"
                     /note="glucarate dehydratase; TIGR03247"
                     /db_xref="CDD:211799"
ORIGIN      
        1 mttfsstpvv ttmqvipvag hdsmlmnlsg ahapyftrni viikdnaght gvgeipggek
       61 irqtledaip lvvgktlgey knvlgavrnq fadrdaggrg lqtfdlrtti hvvtgieaal
      121 ldllgqhlgv nvasllgdgq qrsevemlgy lffvgnrhat playqsqpde qcewyrlrhe
      181 eamtpdavvr laeaayekyg fndfklkggv lagfeeaeai salakrfpna rvtldpngaw
      241 lleeaiqigk qlkgvlayae dpcgaeqgfs grevmaefrr atglptatnm iatdwrqmgh
      301 tlslqsvdip ladphfwtmq gsvrvaqmch efgltwgshs nnhfdvslam fthvaaaapg
      361 kitaidthwi wqegnqrltk qpfeikggmv qvpstpglgv eldmdrvmqa nelykkhglg
      421 arddamamqy lipgwtfdnk rpcmvr