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LOCUS WP_002915220 434 aa linear BCT 13-MAY-2021 [Klebsiella]. ACCESSION WP_002915220 VERSION WP_002915220.1 KEYWORDS RefSeq. SOURCE Klebsiella ORGANISM Klebsiella Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group. REFERENCE 1 (residues 1 to 434) AUTHORS Hur,S., Stroud,R.M. and Finer-Moore,J. TITLE Substrate recognition by RNA 5-methyluridine methyltransferases and pseudouridine synthases: a structural perspective JOURNAL J. Biol. Chem. 281 (51), 38969-38973 (2006) PUBMED 17085441 REFERENCE 2 (residues 1 to 434) AUTHORS Lee,T.T., Agarwalla,S. and Stroud,R.M. TITLE A unique RNA Fold in the RumA-RNA-cofactor ternary complex contributes to substrate selectivity and enzymatic function JOURNAL Cell 120 (5), 599-611 (2005) PUBMED 15766524 REFERENCE 3 (residues 1 to 434) AUTHORS Agarwalla,S., Stroud,R.M. and Gaffney,B.J. TITLE Redox reactions of the iron-sulfur cluster in a ribosomal RNA methyltransferase, RumA: optical and EPR studies JOURNAL J. Biol. Chem. 279 (33), 34123-34129 (2004) PUBMED 15181002 REFERENCE 4 (residues 1 to 434) AUTHORS Lee,T.T., Agarwalla,S. and Stroud,R.M. TITLE Crystal structure of RumA, an iron-sulfur cluster containing E. coli ribosomal RNA 5-methyluridine methyltransferase JOURNAL Structure 12 (3), 397-407 (2004) PUBMED 15016356 REFERENCE 5 (residues 1 to 434) AUTHORS Madsen,C.T., Mengel-Jorgensen,J., Kirpekar,F. and Douthwaite,S. TITLE Identifying the methyltransferases for m(5)U747 and m(5)U1939 in 23S rRNA using MALDI mass spectrometry JOURNAL Nucleic Acids Res. 31 (16), 4738-4746 (2003) PUBMED 12907714 REFERENCE 6 (residues 1 to 434) AUTHORS Agarwalla,S., Kealey,J.T., Santi,D.V. and Stroud,R.M. TITLE Characterization of the 23 S ribosomal RNA m5U1939 methyltransferase from Escherichia coli JOURNAL J. Biol. Chem. 277 (11), 8835-8840 (2002) PUBMED 11779873 COMMENT REFSEQ: This record represents a single, non-redundant, protein sequence which may be annotated on many different RefSeq genomes from the same, or different, species. ##Evidence-For-Name-Assignment-START## Evidence Category :: HMM Evidence Accession :: NF009639.0 Evidence Source :: NCBI Protein Cluster (PRK) Source Identifier :: PRK13168 ##Evidence-For-Name-Assignment-END## COMPLETENESS: full length. FEATURES Location/Qualifiers source 1..434 /organism="Klebsiella" /db_xref="taxon:570" gene 1..434 /gene="rlmD" Protein 1..434 /product="23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD" /EC_number="2.1.1.190" /GO_function="GO:0008173 - RNA methyltransferase activity [Evidence IEA]" /GO_process="GO:0006396 - RNA processing [Evidence IEA]" /calculated_mol_wt=48338 Region 2..432 /region_name="rumA" /note="23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD; PRK13168" /db_xref="CDD:237291" ORIGIN 1 maqfysakrr vttrqiitvt vndldpfgqg varhqgkalf vsgvlpheqa evalvedkkq 61 yaraevkrrl tdspqrqapr cphfgvcggc qqqhasvplq qqskraalgr lmkrevddvi 121 agapwgyrrr arlslnyqpk tqqlqmgfrq anakaivdvv qcpvlvpqle allpavrecl 181 salsalrhlg hvelvqadng plmvlrhtaa lpatdrekle rfsqthglsl ylapqseile 241 hihgeapwyt sdglrlvfsp rdfiqvndgv nqqmvrtale wldlrpedrv ldlfcgmgnf 301 tlplatraah vvgvegvpal vekgrenaar nglsnvtffh enleedvtrq awakhgfdkv 361 lldparagap gvmphiikla prrvvyvscn patlardset llqagyqiqr lamldmfpht 421 ghlesmvlfe rrlt