Unfortunately due to lack of commercial feasibility, the SkyBLAST service has been suspended from December 1st, 2025.
All subscriptions for paid accounts have been paused. For further information or enquiries, please email [email protected]

MULTISPECIES: LacI family DNA-binding transcriptional regulator


LOCUS       WP_002914876             337 aa            linear   BCT 23-JUL-2024
            [Klebsiella].
ACCESSION   WP_002914876
VERSION     WP_002914876.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 337)
  AUTHORS   Fukami-Kobayashi,K., Tateno,Y. and Nishikawa,K.
  TITLE     Parallel evolution of ligand specificity between LacI/GalR family
            repressors and periplasmic sugar-binding proteins
  JOURNAL   Mol Biol Evol 20 (2), 267-277 (2003)
   PUBMED   12598694
REFERENCE   2  (residues 1 to 337)
  AUTHORS   Nguyen,C.C. and Saier,M.H. Jr.
  TITLE     Phylogenetic, structural and functional analyses of the LacI-GalR
            family of bacterial transcription factors
  JOURNAL   FEBS Lett 377 (2), 98-102 (1995)
   PUBMED   8543068
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 11446715
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..337
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     Protein         1..337
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription
                     factor activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /calculated_mol_wt=36865
     Region          1..330
                     /region_name="PurR"
                     /note="DNA-binding transcriptional regulator, LacI/PurR
                     family [Transcription]; COG1609"
                     /db_xref="CDD:441217"
ORIGIN      
        1 matmlevakr agvskatvsr vlsgngyvsq etkdrvfkav aesgyrpnll arnlatkttq
       61 tlglvvtntl yhgvyfsell yhvarmtedk grqliladgk hsaqeereai qylldlrcda
      121 iiiyprfltv demdeivenh sqpimvlnrr lrrhashcvw sdqkasamrv verlialghr
      181 niafitgsld sptgverlag ykdalaghgi alnealiaeg rwtpetgaag veslrkrgvt
      241 ysalvasndd maigamkqlh qlgvkvpeqv svvgfddial apymvpslas vrvpvtemik
      301 esinrlifml dggefnfqqs fpgalieres lvagpca