MULTISPECIES: class 1b ribonucleoside-diphosphate reductase subunit

LOCUS       WP_002914327             320 aa            linear   BCT 17-JUN-2024
            beta [Enterobacterales].
ACCESSION   WP_002914327
VERSION     WP_002914327.1
KEYWORDS    RefSeq.
SOURCE      Enterobacterales
  ORGANISM  Enterobacterales
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria.
REFERENCE   1  (residues 1 to 320)
  AUTHORS   Zhang,Y. and Stubbe,J.
  TITLE     Bacillus subtilis class Ib ribonucleotide reductase is a
            dimanganese(III)-tyrosyl radical enzyme
  JOURNAL   Biochemistry 50 (25), 5615-5623 (2011)
   PUBMED   21561096
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR04171.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..320
                     /organism="Enterobacterales"
                     /db_xref="taxon:91347"
     gene            1..320
                     /gene="nrdF"
     Protein         1..320
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /EC_number="1.17.4.1"
                     /GO_component="GO:0005971 - ribonucleoside-diphosphate
                     reductase complex [Evidence IEA]"
                     /GO_function="GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA]"
                     /GO_process="GO:0009263 - deoxyribonucleotide biosynthetic
                     process [Evidence IEA]"
                     /calculated_mol_wt=36009
     Region          7..320
                     /region_name="RNR_1b_NrdF"
                     /note="ribonucleoside-diphosphate reductase, class 1b,
                     beta subunit; TIGR04171"
                     /db_xref="CDD:275027"
     Site            order(10,21,28,93..94,97,100..101,104,107,123..124,127)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:153108"
     Site            order(32,68,99,102,106,191..192,196)
                     /site_type="active"
                     /note="putative radical transfer pathway [active]"
                     /db_xref="CDD:153108"
     Site            order(68,99,102,159,193,196)
                     /site_type="other"
                     /note="diiron center [ion binding]"
                     /db_xref="CDD:153108"
     Site            106
                     /site_type="other"
                     /note="tyrosyl radical"
                     /db_xref="CDD:153108"
ORIGIN      
        1 mthltrvsai nwnridddkd levwnrltsn fwlpekvpls ndipawqtls aaeqqltirv
       61 ftgltlldti qntvgapalm adaltpheea vlsnisfmea vharsyssif stlchskevd
      121 aafawsescd plqrkaqlml gyyqadeplk kkiasvfles flfysgfwlp myfssrgklt
      181 ntadlirlii rdeavhgyyi gykyqkglei vspgkreelk nfaldllmdl ydnelaysre
      241 lygesgwfdd vsaflcynan kalmnlgyea lfpaemaavn pailaalspn adenhdffsg
      301 sgssyvigkm eetadddwdf