MULTISPECIES: bifunctional chorismate mutase/prephenate

LOCUS       WP_002914113             373 aa            linear   BCT 21-APR-2023
            dehydrogenase [Klebsiella].
ACCESSION   WP_002914113
VERSION     WP_002914113.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 373)
  AUTHORS   Chiu,H.J., Abdubek,P., Astakhova,T., Axelrod,H.L., Carlton,D.,
            Clayton,T., Das,D., Deller,M.C., Duan,L., Feuerhelm,J., Grant,J.C.,
            Grzechnik,A., Han,G.W., Jaroszewski,L., Jin,K.K., Klock,H.E.,
            Knuth,M.W., Kozbial,P., Krishna,S.S., Kumar,A., Marciano,D.,
            McMullan,D., Miller,M.D., Morse,A.T., Nigoghossian,E., Okach,L.,
            Reyes,R., Tien,H.J., Trame,C.B., van den Bedem,H., Weekes,D.,
            Xu,Q., Hodgson,K.O., Wooley,J., Elsliger,M.A., Deacon,A.M.,
            Godzik,A., Lesley,S.A. and Wilson,I.A.
  TITLE     The structure of Haemophilus influenzae prephenate dehydrogenase
            suggests unique features of bifunctional TyrA enzymes
  JOURNAL   Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 66 (Pt 10),
            1317-1325 (2010)
   PUBMED   20944228
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF008400.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK11199
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..373
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     gene            1..373
                     /gene="tyrA"
     Protein         1..373
                     /product="bifunctional chorismate mutase/prephenate
                     dehydrogenase"
                     /EC_number="1.3.1.12"
                     /EC_number="5.4.99.5"
                     /GO_function="GO:0004106 - chorismate mutase activity
                     [Evidence IEA]"
                     /GO_function="GO:0004665 - prephenate dehydrogenase
                     (NADP+) activity [Evidence IEA]"
                     /GO_function="GO:0008977 - prephenate dehydrogenase (NAD+)
                     activity [Evidence IEA]"
                     /GO_process="GO:0006571 - tyrosine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0046417 - chorismate metabolic process
                     [Evidence IEA]"
                     /calculated_mol_wt=41710
     Region          1..373
                     /region_name="tyrA"
                     /note="bifunctional chorismate mutase/prephenate
                     dehydrogenase; Provisional; PRK11199"
                     /db_xref="CDD:183035"
ORIGIN      
        1 mvaeltalrd qidevdkall sllakrlelv aevgevksqy glpiyvpere samlasrree
       61 aaalgvppdl iedvlrrvmr esyssendkg fktlqpnlrp vvivggggqm grlfekmltl
      121 sgyqvrilek ndwaraadiv adagmvivsv pihttvetig rlpplpadci lvdlasvkae
      181 plqamlaahq gpvlglhpmf gpdsgslakq vvvycdgrqp eayqwfleqi qvwgarlhri
      241 savehdqnma fiqalrhfat fayglhlaee nvrleqllal sspiyrlela mvgrlfaqdp
      301 qlyadiimss ennlalikry yqrfgeaigl leqgdkqafi dsfrkvehwf gdyaqrfqse
      361 srtllrqand nrq