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LOCUS WP_002914044 473 aa linear BCT 23-DEC-2024 ACCESSION WP_002914044 VERSION WP_002914044.1 KEYWORDS RefSeq. SOURCE Klebsiella ORGANISM Klebsiella Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group. REFERENCE 1 (residues 1 to 473) AUTHORS Laub,M.T. and Goulian,M. TITLE Specificity in two-component signal transduction pathways JOURNAL Annu Rev Genet 41, 121-145 (2007) PUBMED 18076326 REFERENCE 2 (residues 1 to 473) AUTHORS Hoch,J.A. and Varughese,K.I. TITLE Keeping signals straight in phosphorelay signal transduction JOURNAL J Bacteriol 183 (17), 4941-4949 (2001) PUBMED 11489844 REFERENCE 3 (residues 1 to 473) AUTHORS West,A.H. and Stock,A.M. TITLE Histidine kinases and response regulator proteins in two-component signaling systems JOURNAL Trends Biochem Sci 26 (6), 369-376 (2001) PUBMED 11406410 REFERENCE 4 (residues 1 to 473) AUTHORS Stock,A.M., Robinson,V.L. and Goudreau,P.N. TITLE Two-component signal transduction JOURNAL Annu Rev Biochem 69, 183-215 (2000) PUBMED 10966457 REFERENCE 5 (residues 1 to 473) AUTHORS Stock,J. TITLE Signal transduction: Gyrating protein kinases JOURNAL Curr Biol 9 (10), R364-R367 (1999) PUBMED 10339418 REFERENCE 6 (residues 1 to 473) AUTHORS Alex,L.A. and Simon,M.I. TITLE Protein histidine kinases and signal transduction in prokaryotes and eukaryotes JOURNAL Trends Genet 10 (4), 133-138 (1994) PUBMED 8029829 COMMENT REFSEQ: This record represents a single, non-redundant, protein sequence which may be annotated on many different RefSeq genomes from the same, or different, species. ##Evidence-For-Name-Assignment-START## Evidence Category :: Conserved Domain (CDD) Evidence Accession :: Domain architecture ID 18747083 Evidence Source :: NCBI SPARCLE ##Evidence-For-Name-Assignment-END## COMPLETENESS: full length. FEATURES Location/Qualifiers source 1..473 /organism="Klebsiella" /db_xref="taxon:570" Protein 1..473 /product="sensor histidine kinase" /EC_number="2.7.13.3" /GO_function="GO:0000155 - phosphorelay sensor kinase activity [Evidence IEA]" /GO_function="GO:0000156 - phosphorelay response regulator activity [Evidence IEA]" /GO_function="GO:0004673 - protein histidine kinase activity [Evidence IEA]" /GO_function="GO:0005524 - ATP binding [Evidence IEA]" /GO_process="GO:0007165 - signal transduction [Evidence IEA]" /calculated_mol_wt=52731 Region 1..473 /region_name="COG4251" /note="Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal transduction mechanisms]" /db_xref="CDD:443393" Region 241..473 /region_name="KdpD" /note="K+-sensing histidine kinase KdpD [Signal transduction mechanisms]; COG2205" /db_xref="CDD:441807" ORIGIN 1 mkrlslfprs lrqlvtlsfv lillpllvla wqawqslnal saqaahinrt tlvdarrsea 61 minaalemer syrqycvldd ptlarvyqnq rqrysqmlda hagvlpdekl wqalrqdvsd 121 laqlqcknsg pdaqaaarle vfasnnsdmv qatravvysr gqqlqqeiae rgqffgwqal 181 vlfllslalv llftrmiigp vkgierminq lgagksldda alftgprelr svgkriiwls 241 erlawlesqr hqflrhlshe lktplasmre gtelladrva gpltpeqqei veildsssrn 301 lqklieqlld ynrkqadgpv areavdlvdl venvvaahsl paraklmhte ltlqarrcla 361 epallisvmd nlysnavhyg aesgnirihs yrhgeqvrid vansgepipa aeknmifepf 421 yqgshqrkga vkgsglglsi ardcvrqmqg elslvdapag qvcfritlps ape