MULTISPECIES: AI-2E family transporter [Klebsiella].

LOCUS       WP_002913806             353 aa            linear   BCT 31-DEC-2024
ACCESSION   WP_002913806
VERSION     WP_002913806.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 353)
  AUTHORS   Khera,R., Mehdipour,A.R., Bolla,J.R., Kahnt,J., Welsch,S.,
            Ermler,U., Muenke,C., Robinson,C.V., Hummer,G., Xie,H. and
            Michel,H.
  TITLE     Cryo-EM structures of pentameric autoinducer-2 exporter from
            Escherichia coli reveal its transport mechanism
  JOURNAL   EMBO J 41 (18), e109990 (2022)
   PUBMED   35698912
REFERENCE   2  (residues 1 to 353)
  AUTHORS   Rettner,R.E. and Saier,M.H. Jr.
  TITLE     The autoinducer-2 exporter superfamily
  JOURNAL   J Mol Microbiol Biotechnol 18 (4), 195-205 (2010)
   PUBMED   20559013
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10001851
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..353
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     Protein         1..353
                     /product="AI-2E family transporter"
                     /GO_function="GO:0015562 - efflux transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport
                     [Evidence IEA]"
                     /GO_process="GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /calculated_mol_wt=39090
     Region          18..347
                     /region_name="PerM"
                     /note="Predicted PurR-regulated permease PerM [General
                     function prediction only]; COG0628"
                     /db_xref="CDD:440393"
ORIGIN      
        1 mlemlmqwyr rrfsdpeaia llvillagfg imfffsglla pllvaivlay llewptvrle
       61 riglsrtwat slvlilfvgi llllafvvlp vawqqgiyli rdmpgmlnkl sdfaatlprr
      121 ypalmdagii damaenmrtr mltvgdsvvk yslaslvgll tlavylvlvp lmvffllkdk
      181 eqmlnavrrv lprnrglagq vwkemnqqit nyirgkvlem ivvsvatwig filfglnysl
      241 llavlvgfsv lipyigafvv tipvvgvalf qfgagtefws lfavyliiqg ldgnllvpvl
      301 fseavnlhpl viilsvvifg glwgfwgvff aiplatlika vvhawpdgla vdd