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MULTISPECIES: succinyl-diaminopimelate desuccinylase [Klebsiella].


LOCUS       WP_002913766             375 aa            linear   BCT 08-JUL-2020
ACCESSION   WP_002913766
VERSION     WP_002913766.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 375)
  AUTHORS   Davis,R., Bienvenue,D., Swierczek,S.I., Gilner,D.M., Rajagopal,L.,
            Bennett,B. and Holz,R.C.
  TITLE     Kinetic and spectroscopic characterization of the E134A- and
            E134D-altered dapE-encoded N-succinyl-L,L-diaminopimelic acid
            desuccinylase from Haemophilus influenzae
  JOURNAL   J. Biol. Inorg. Chem. 11 (2), 206-216 (2006)
   PUBMED   16421726
REFERENCE   2  (residues 1 to 375)
  AUTHORS   Bienvenue,D.L., Gilner,D.M., Davis,R.S., Bennett,B. and Holz,R.C.
  TITLE     Substrate specificity, metal binding properties, and spectroscopic
            characterization of the DapE-encoded N-succinyl-L,L-diaminopimelic
            acid desuccinylase from Haemophilus influenzae
  JOURNAL   Biochemistry 42 (36), 10756-10763 (2003)
   PUBMED   12962500
REFERENCE   3  (residues 1 to 375)
  AUTHORS   Broder,D.H. and Miller,C.G.
  TITLE     DapE can function as an aspartyl peptidase in the presence of Mn2+
  JOURNAL   J. Bacteriol. 185 (16), 4748-4754 (2003)
   PUBMED   12896993
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF009557.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK13009
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..375
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     gene            1..375
                     /gene="dapE"
     Protein         1..375
                     /product="succinyl-diaminopimelate desuccinylase"
                     /EC_number="3.5.1.18"
                     /GO_function="GO:0009014 - succinyl-diaminopimelate
                     desuccinylase activity [Evidence IEA]"
                     /GO_process="GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /calculated_mol_wt=41239
     Region          2..375
                     /region_name="PRK13009"
                     /note="succinyl-diaminopimelate desuccinylase; Reviewed"
                     /db_xref="CDD:237265"
     Site            order(182,193..196,202,204..205,208..209,211..212,215,230,
                     232..239,246..247,255,257,322)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:349886"
ORIGIN      
        1 mscpvielaq qlirrpslsp ddagcqalmi erlraigftv epmdfgdtqn fwawrghget
       61 lafaghtdvv pagdadrwin ppfeptirdg mlfgrgaadm kgslaamvva aerfvaqypn
      121 hrgrlaflit sdeeasakng tvkvvetlma rnerldyclv gepsstevvg dvvkngrrgs
      181 ltcnltihgv qghvayphla dnpvhraapm laelvniewd kgneffppts mqianvqsgt
      241 gsnnvipgdm fvqfnfrfst eltdemiksr viallekyql rysvewwlsg qpfltgrgkl
      301 vdavvnaieh yneikpqllt nggtsdgrfi armgaqvvel gpvnatihki necvnaadlq
      361 llarmyqrvm eqlva