MULTISPECIES: chorismate synthase [Klebsiella].

LOCUS       WP_002913342             361 aa            linear   BCT 20-NOV-2023
ACCESSION   WP_002913342
VERSION     WP_002913342.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 361)
  AUTHORS   Viola,C.M., Saridakis,V. and Christendat,D.
  TITLE     Crystal structure of chorismate synthase from Aquifex aeolicus
            reveals a novel beta alpha beta sandwich topology
  JOURNAL   Proteins 54 (1), 166-169 (2004)
   PUBMED   14705034
REFERENCE   2  (residues 1 to 361)
  AUTHORS   Ahn,H.J., Yang,J.K., Lee,B.I., Yoon,H.J., Kim,H.W. and Suh,S.W.
  TITLE     Crystallization and preliminary X-ray crystallographic studies of
            chorismate synthase from Helicobacter pylori
  JOURNAL   Acta Crystallogr. D Biol. Crystallogr. 59 (Pt 3), 569-571 (2003)
   PUBMED   12595729
REFERENCE   3  (residues 1 to 361)
  AUTHORS   Fitzpatrick,T.B., Killer,P., Thomas,R.M., Jelesarov,I., Amrhein,N.
            and Macheroux,P.
  TITLE     Chorismate synthase from the hyperthermophile Thermotoga maritima
            combines thermostability and increased rigidity with catalytic and
            spectral properties similar to mesophilic counterparts
  JOURNAL   J. Biol. Chem. 276 (21), 18052-18059 (2001)
   PUBMED   11279147
REFERENCE   4  (residues 1 to 361)
  AUTHORS   Horsburgh,M.J., Foster,T.J., Barth,P.T. and Coggins,J.R.
  TITLE     Chorismate synthase from Staphylococcus aureus
  JOURNAL   Microbiology (Reading, Engl.) 142 (Pt 10), 2943-2950 (1996)
   PUBMED   8885411
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF003793.1
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK05382
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..361
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     gene            1..361
                     /gene="aroC"
     Protein         1..361
                     /product="chorismate synthase"
                     /EC_number="4.2.3.5"
                     /GO_function="GO:0004107 - chorismate synthase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /calculated_mol_wt=38877
     Region          8..361
                     /region_name="PRK05382"
                     /note="chorismate synthase; Validated"
                     /db_xref="CDD:235438"
     Site            order(11..17,24,26,28,32..33,66..67,69..70,77..78,80,82,
                     84,111..115,125..126,134,196,201..206,217,219..221,225,
                     227..228,231..233,235..236,238,241..245,248..249,251..252,
                     256..257,273,276..278,280..282,289,291..294,297,335)
                     /site_type="other"
                     /note="Tetramer interface [polypeptide binding]"
                     /db_xref="CDD:143612"
     Site            order(19,48,105..106,126..129,132,238..239,292..293,
                     295..297,324,328)
                     /site_type="active"
                     /db_xref="CDD:143612"
     Site            order(105..107,125,127,237..239,293,295..297,321,324,327)
                     /site_type="other"
                     /note="FMN-binding site [chemical binding]"
                     /db_xref="CDD:143612"
ORIGIN      
        1 magntigqlf rvttfgeshg lalgcivdgv ppgipltead lqhdldrrrp gtsryttqrr
       61 epdqvkilsg vfegvttgts igllientdq rsqdygaikd lfrpghadyt yeqkyglrdy
      121 rgggrssare tamrvaagai akkylaakfg ivirgcltqm gdiplaikdw dqveqnpffc
      181 pdpdkidald elmrglkkeg dsigakvtvv adgvppglge pvfdrldadi ahalmsinav
      241 kgveigdgfe vvklrgsenr deitkagfqs nhaggilggi ssgqqivani alkptssitv
      301 pghtinrfge evemitkgrh dpcvgiravp iaeamlaivl mdhfmrqraq ngdvtttipr
      361 w