MULTISPECIES: tRNA pseudouridine(38-40) synthase TruA [Klebsiella].

LOCUS       WP_002913226             270 aa            linear   BCT 23-MAY-2024
ACCESSION   WP_002913226
VERSION     WP_002913226.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 270)
  AUTHORS   Hur,S. and Stroud,R.M.
  TITLE     How U38, 39, and 40 of many tRNAs become the targets for
            pseudouridylation by TruA
  JOURNAL   Mol Cell 26 (2), 189-203 (2007)
   PUBMED   17466622
REFERENCE   2  (residues 1 to 270)
  AUTHORS   Dong,X., Bessho,Y., Shibata,R., Nishimoto,M., Shirouzu,M.,
            Kuramitsu,S. and Yokoyama,S.
  TITLE     Crystal structure of tRNA pseudouridine synthase TruA from Thermus
            thermophilus HB8
  JOURNAL   RNA Biol 3 (3), 115-122 (2006)
   PUBMED   17114947
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR00071.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..270
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     gene            1..270
                     /gene="truA"
     Protein         1..270
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /EC_number="5.4.99.12"
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /GO_function="GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA]"
                     /GO_process="GO:0001522 - pseudouridine synthesis
                     [Evidence IEA]"
                     /GO_process="GO:0009451 - RNA modification [Evidence IEA]"
                     /calculated_mol_wt=30171
     Region          11..258
                     /region_name="TruA"
                     /note="tRNA U38,U39,U40 pseudouridine synthase TruA
                     [Translation, ribosomal structure and biogenesis];
                     COG0101"
                     /db_xref="CDD:439871"
ORIGIN      
        1 msemeqqpic kialgieydg skyygwqrqn evrsvqekle kalsqvanep itvfcagrtd
       61 agvhgtgqvv hfetraqrkd aawtlgvnan lpgdiavrwv khvpadfhar fsatarryry
      121 viynhrlrpa vlshgvthfh qpldaermqr aaqcllgend ftsfravqcq srtpwrnvmh
      181 invtrygayv vvdikanafv hhmvrnivgs lmevgagnqp eswmaellaa kdrtlaaata
      241 kaeglylvsv dypahydlpv lpmgplflad