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MULTISPECIES: bifunctional tetrahydrofolate synthase/dihydrofolate


LOCUS       WP_002913219             422 aa            linear   BCT 08-JUL-2020
            synthase [Klebsiella].
ACCESSION   WP_002913219
VERSION     WP_002913219.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF008101.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK10846
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     gene            1..422
                     /gene="folC"
     Protein         1..422
                     /product="bifunctional tetrahydrofolate
                     synthase/dihydrofolate synthase"
                     /EC_number="6.3.2.12"
                     /EC_number="6.3.2.17"
                     /GO_function="GO:0004326 - tetrahydrofolylpolyglutamate
                     synthase activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016874 - ligase activity [Evidence IEA]"
                     /GO_process="GO:0009396 - folic acid-containing compound
                     biosynthetic process [Evidence IEA]"
                     /calculated_mol_wt=44940
     Region          1..416
                     /region_name="PRK10846"
                     /note="bifunctional folylpolyglutamate synthase/
                     dihydrofolate synthase; Provisional"
                     /db_xref="CDD:182774"
ORIGIN      
        1 mekdpipqat splatwlsyl ehlhsktidl glarvsevag qmdivkpapf vftvagtngk
       61 gttcrtleti lmaagykvgv yssphlvryt ervriqgael peaahtasfa eieaargdis
      121 ltyfeygtls alwlfkqaql dvvilevglg grldatnivd advavvtsia ldhtdwlgpd
      181 resigrekag ifragkpavv gepdmpltia evasekgall qrrgvdwrye vegetwsfrd
      241 tagalshlpl pqvplpnaat avaalrasgl avddailrag irdamlpgrf qiisdaprvi
      301 ldvahnphaa aylagrlktl aktgrvlavi gmlhdkdiag tlanlapevd awycaplegp
      361 rgataeqlve hlrcgtvyss vaqawraama dakvedtvlv cgsfhtvaqv meeidagrig
      421 ge