MULTISPECIES: histidine ABC transporter permease HisM [Klebsiella].

LOCUS       WP_002913207             238 aa            linear   BCT 20-NOV-2023
ACCESSION   WP_002913207
VERSION     WP_002913207.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 238)
  AUTHORS   Heuveling,J., Frochaux,V., Ziomkowska,J., Wawrzinek,R., Wessig,P.,
            Herrmann,A. and Schneider,E.
  TITLE     Conformational changes of the bacterial type I ATP-binding cassette
            importer HisQMP2 at distinct steps of the catalytic cycle
  JOURNAL   Biochim. Biophys. Acta 1838 (1 Pt B), 106-116 (2014)
   PUBMED   24021237
REFERENCE   2  (residues 1 to 238)
  AUTHORS   Liu,P.Q. and Ames,G.F.
  TITLE     In vitro disassembly and reassembly of an ABC transporter, the
            histidine permease
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 95 (7), 3495-3500 (1998)
   PUBMED   9520394
REFERENCE   3  (residues 1 to 238)
  AUTHORS   Kerppola,R.E., Shyamala,V.K., Klebba,P. and Ames,G.F.
  TITLE     The membrane-bound proteins of periplasmic permeases form a
            complex. Identification of the histidine permease HisQMP complex
  JOURNAL   J. Biol. Chem. 266 (15), 9857-9865 (1991)
   PUBMED   2033074
REFERENCE   4  (residues 1 to 238)
  AUTHORS   Higgins,C.F., Haag,P.D., Nikaido,K., Ardeshir,F., Garcia,G. and
            Ames,G.F.
  TITLE     Complete nucleotide sequence and identification of membrane
            components of the histidine transport operon of S. typhimurium
  JOURNAL   Nature 298 (5876), 723-727 (1982)
   PUBMED   7050725
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR011227
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..238
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     gene            1..238
                     /gene="hisM"
     Protein         1..238
                     /product="histidine ABC transporter permease HisM"
                     /calculated_mol_wt=26517
     Region          1..234
                     /region_name="PRK15069"
                     /note="histidine ABC transporter permease HisM"
                     /db_xref="CDD:185029"
     Site            order(39..40,43..44,49,59..62,64..73,76..77,79,111..112,
                     114,116,119..120,122,126..127,130,147,161..162,165,
                     172..175,178..179,192..193,203..204,207..208,210..211,
                     214..215,218)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:119394"
     Site            order(65..79,172..177)
                     /site_type="active"
                     /note="conserved gate region [active]"
                     /db_xref="CDD:119394"
     Site            order(79,106,178,190,193,203)
                     /site_type="active"
                     /note="putative PBP binding loops [active]"
                     /db_xref="CDD:119394"
     Site            order(131..143,149..150,154)
                     /site_type="active"
                     /note="ABC-ATPase subunit interface [active]"
                     /db_xref="CDD:119394"
ORIGIN      
        1 mieiiqeywk sllwtdgyrf tgvaitlwll issvvmggil avflaigrvs snkfiqfpiw
       61 lftyifrgtp lyvqllvfys gmytleivkg tellnaffrs glnctvlalt lntcayttei
      121 fagairsvpa geieaarayg fssvklyrci ilpsalrial paysnevilm lhstalafta
      181 tvpdllkiar dinsatyqpf tafgiaavly liisyvlisl frkaekrwlq hikpssth