MULTISPECIES:

LOCUS       WP_002913103             556 aa            linear   BCT 04-JUN-2024
            2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid
            synthase [Klebsiella].
ACCESSION   WP_002913103
VERSION     WP_002913103.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 556)
  AUTHORS   Jiang,M., Cao,Y., Guo,Z.F., Chen,M., Chen,X. and Guo,Z.
  TITLE     Menaquinone biosynthesis in Escherichia coli: identification of
            2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate as a
            novel intermediate and re-evaluation of MenD activity
  JOURNAL   Biochemistry 46 (38), 10979-10989 (2007)
   PUBMED   17760421
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR00173.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..556
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     gene            1..556
                     /gene="menD"
     Protein         1..556
                     /product="2-succinyl-5-enolpyruvyl-6-hydroxy-3-
                     cyclohexene-1-carboxylic-acid synthase"
                     /EC_number="2.2.1.9"
                     /GO_function="GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA]"
                     /GO_function="GO:0070204 -
                     2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-
                     carboxylic-acid synthase activity [Evidence IEA]"
                     /GO_process="GO:0009234 - menaquinone biosynthetic process
                     [Evidence IEA]"
                     /calculated_mol_wt=60459
     Region          2..556
                     /region_name="MenD"
                     /note="2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-
                     carboxylate synthase [Coenzyme transport and metabolism];
                     COG1165"
                     /db_xref="CDD:440779"
ORIGIN      
        1 msvsafnrrw aavilealtr hgvqhiciap gsrstpltla aaenrafihh thfderglgh
       61 lalglakasr qpvavivtsg tatanlypal ieagltgekl illtadrppe lidcganqai
      121 rqpgmfashp aqtislprps qdiparwlvs tidqalgalh aggvhincpf aeplygdmde
      181 tgvewqqqlg nwwqsdkpwl rqalqlesek qrdwffwrqk rgvvvagrms aaegkkvaew
      241 aqtlgwplig dvlsqtgqpl pcadlwlgng kavselaqaq ivvqlgsslt gkrvlqwqat
      301 cepdeywlvd nlpgrldpaq hrgrrllssv erwlelhpae krqpwatvip qlagqawqaa
      361 vasnepfgea qlaqrirgyl peqgqlfvgn slvvrlidal aqlpagypvy snrgasgidg
      421 liataagvqr asarptlaiv gdlsalydln slallrqasa plvlivvnnn ggqifsmlpt
      481 pqderrqfyl mpqdvdfsha aamfglayhr pddwpsldea lagawrraga tvielavnet
      541 dgaqtlqqll aqvsrl