MULTISPECIES: bifunctional 2-polyprenyl-6-hydroxyphenol

LOCUS       WP_002913014             242 aa            linear   BCT 11-FEB-2024
            methylase/3-demethylubiquinol 3-O-methyltransferase UbiG
            [Enterobacteriaceae].
ACCESSION   WP_002913014
VERSION     WP_002913014.1
KEYWORDS    RefSeq.
SOURCE      Enterobacteriaceae
  ORGANISM  Enterobacteriaceae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales.
REFERENCE   1  (residues 1 to 242)
  AUTHORS   Meganathan,R.
  TITLE     Ubiquinone biosynthesis in microorganisms
  JOURNAL   FEMS Microbiol Lett 203 (2), 131-139 (2001)
   PUBMED   11583838
REFERENCE   2  (residues 1 to 242)
  AUTHORS   Poon,W.W., Barkovich,R.J., Hsu,A.Y., Frankel,A., Lee,P.T.,
            Shepherd,J.N., Myles,D.C. and Clarke,C.F.
  TITLE     Yeast and rat Coq3 and Escherichia coli UbiG polypeptides catalyze
            both O-methyltransferase steps in coenzyme Q biosynthesis
  JOURNAL   J Biol Chem 274 (31), 21665-21672 (1999)
   PUBMED   10419476
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR01983.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..242
                     /organism="Enterobacteriaceae"
                     /db_xref="taxon:543"
     gene            1..242
                     /gene="ubiG"
     Protein         1..242
                     /product="bifunctional 2-polyprenyl-6-hydroxyphenol
                     methylase/3-demethylubiquinol 3-O-methyltransferase UbiG"
                     /EC_number="2.1.1.222"
                     /EC_number="2.1.1.64"
                     /GO_function="GO:0061542 - 3-demethylubiquinol-n
                     3-O-methyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0006744 - ubiquinone biosynthetic process
                     [Evidence IEA]"
                     /calculated_mol_wt=26520
     Region          16..234
                     /region_name="UbiG"
                     /note="ubiquinone biosynthesis O-methyltransferase;
                     TIGR01983"
                     /db_xref="CDD:273910"
     Site            order(63..69,85..86,110..112,129)
                     /site_type="other"
                     /note="S-adenosylmethionine binding site [chemical
                     binding]"
                     /db_xref="CDD:100107"
ORIGIN      
        1 mnaektsvap nvdhaeiakf eavasrwwdl egefkplhri nplrlgyiae rsgglfgkkv
       61 ldvgcgggil aesmaregat vtgldmgaep lqvarlhale sgiqvdyvqe tveehaakhp
      121 qqydvvtcme mlehvpdpqs vvhacarlvk pggqvffsti nrngkawlma vvgaeyvmkm
      181 vpkgthdvkk fikpaellgw vdqttlkeqh iiglhynplt ntfklapgvd vnymlhttak
      241 qd