MULTISPECIES: DNA topoisomerase (ATP-hydrolyzing) subunit A

LOCUS       WP_002913012             877 aa            linear   BCT 02-DEC-2022
            [Klebsiella].
ACCESSION   WP_002913012
VERSION     WP_002913012.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR01063.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..877
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     gene            1..877
                     /gene="gyrA"
     Protein         1..877
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit A"
                     /EC_number="5.6.2.2"
                     /GO_component="GO:0009330 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) complex [Evidence
                     IEA]"
                     /GO_function="GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA]"
                     /GO_function="GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA]"
                     /GO_process="GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /calculated_mol_wt=96851
     Region          7..842
                     /region_name="PRK05560"
                     /note="DNA gyrase subunit A; Validated"
                     /db_xref="CDD:235502"
     Region          538..585
                     /region_name="GyrA_CTD repeat"
                     /note="GyrA_CTD repeat [structural motif]"
                     /db_xref="CDD:293790"
     Region          588..638
                     /region_name="GyrA_CTD repeat"
                     /note="GyrA_CTD repeat [structural motif]"
                     /db_xref="CDD:293790"
     Region          644..688
                     /region_name="GyrA_CTD repeat"
                     /note="GyrA_CTD repeat [structural motif]"
                     /db_xref="CDD:293790"
     Region          692..739
                     /region_name="GyrA_CTD repeat"
                     /note="GyrA_CTD repeat [structural motif]"
                     /db_xref="CDD:293790"
     Region          742..790
                     /region_name="GyrA_CTD repeat"
                     /note="GyrA_CTD repeat [structural motif]"
                     /db_xref="CDD:293790"
     Region          <828..877
                     /region_name="FYDLN_acid"
                     /note="Protein of unknown function (FYDLN_acid); cl19417"
                     /db_xref="CDD:450301"
ORIGIN      
        1 msdlareitp vnieeelkns yldyamsviv gralpdvrdg lkpvhrrvly amnvlgndwn
       61 kaykksarvv gdvigkyhph gdiavydtiv rmaqpfslry mlvdgqgnfg sidgdsaaam
      121 ryteirlaki ahelmadlek etvdfvdnyd gteripdvmp tkipnllvng asgiavgmat
      181 nipphnltev ingclayvdd edisieglma hipgpdfpta aiingrrgie eayrtgrgkv
      241 yiraraevev daksgretii vheipyqvnk arliekiael vkekrvegis alrdesdkdg
      301 mrivievkrd avgevvlnnl ysqtqlqvsf ginmvalhhg qpkimnlkdi iaafvrhrre
      361 vvtrrtifel rkardrahil ealavalani dpiielirra ptpaeaktal vaqawdlgnv
      421 aamleragdd aarpewlepe fgvrdgkyyl teqqaqaild lrlqkltgle heklldeyke
      481 lleqiaellh ilgsadrlme vireelelir dqfgderrte itansadini edlinqedvv
      541 vtlshqgyvk yqpltdyeaq rrggkgksaa rikeedfidr llvanthdti lcfssrgrly
      601 wmkvyqlpea srgargrpiv nllpleader itailpvrey eegvnvfmat asgtvkktal
      661 tefsrprsag iiavnlnegd eligvdltsg qdevmlfsaa gkvvrfkeda vramgrtatg
      721 vrgiklaend svvsliiprg egailtvtqn gygkrtaaae yptksratqg visikvtern
      781 gsvvgavqvd dcdqimmitd agtlvrtrvs evsivgrntq gvilirtaed envvglqrva
      841 epvddeelda idgsaaegdd diapeadtdd diaedee