MULTISPECIES: AI-2E family transporter [Klebsiella].

LOCUS       WP_002912992             369 aa            linear   BCT 31-DEC-2024
ACCESSION   WP_002912992
VERSION     WP_002912992.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 369)
  AUTHORS   Khera,R., Mehdipour,A.R., Bolla,J.R., Kahnt,J., Welsch,S.,
            Ermler,U., Muenke,C., Robinson,C.V., Hummer,G., Xie,H. and
            Michel,H.
  TITLE     Cryo-EM structures of pentameric autoinducer-2 exporter from
            Escherichia coli reveal its transport mechanism
  JOURNAL   EMBO J 41 (18), e109990 (2022)
   PUBMED   35698912
REFERENCE   2  (residues 1 to 369)
  AUTHORS   Rettner,R.E. and Saier,M.H. Jr.
  TITLE     The autoinducer-2 exporter superfamily
  JOURNAL   J Mol Microbiol Biotechnol 18 (4), 195-205 (2010)
   PUBMED   20559013
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10001851
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..369
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     Protein         1..369
                     /product="AI-2E family transporter"
                     /GO_function="GO:0015562 - efflux transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport
                     [Evidence IEA]"
                     /GO_process="GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /calculated_mol_wt=39971
     Region          4..351
                     /region_name="PerM"
                     /note="Predicted PurR-regulated permease PerM [General
                     function prediction only]; COG0628"
                     /db_xref="CDD:440393"
ORIGIN      
        1 mrvngltkgf filivfivtl affdvlspyy sailwaaila vifnpvknki rtrlgerngl
       61 aalmtiviic livftplaii lsslayelnl vysklqhndt qfptvvaslf ahlpgwarsf
      121 ladhnldsaq qiqqqlsdaa lkggqylags afligkgtfg ftvsfgimly llffllkdgp
      181 ylvllilesl plssyvkqhl fakfaavara tvkgtvaval aqgalggfaf wiagldgsil
      241 wgalmaflsl ipavgsaiiw vpaaiylfat gqlwqgafiv gffviviglv dnilrpllvg
      301 kdtrmpdyli liatlggmei ygingfvigp liaalfiacw nllsgrehag ntdeideefi
      361 eeaknsrne