MULTISPECIES: GTP cyclohydrolase I FolE [Klebsiella].

LOCUS       WP_002912924             222 aa            linear   BCT 20-NOV-2023
ACCESSION   WP_002912924
VERSION     WP_002912924.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF006824.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK09347
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..222
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     gene            1..222
                     /gene="folE"
     Protein         1..222
                     /product="GTP cyclohydrolase I FolE"
                     /EC_number="3.5.4.16"
                     /GO_function="GO:0003934 - GTP cyclohydrolase I activity
                     [Evidence IEA]"
                     /GO_process="GO:0046654 - tetrahydrofolate biosynthetic
                     process [Evidence IEA]"
                     /calculated_mol_wt=24833
     Region          40..220
                     /region_name="TFold"
                     /note="Tunnelling fold (T-fold). The five known T-folds
                     are found in five different enzymes with different
                     functions: dihydroneopterin-triphosphate epimerase
                     (DHNTPE), dihydroneopterin aldolase (DHNA), GTP
                     cyclohydrolase I (GTPCH-1), 6-pyrovoyl...; cl00263"
                     /db_xref="CDD:469697"
     Site            order(118,120,176,199)
                     /site_type="active"
                     /db_xref="CDD:238349"
ORIGIN      
        1 msslskeavl vhealvargl etpmrapvqe idnetrkrli tghmteimql lnldlsddsl
       61 metphriakm yvdeifsgld ysrfpkitvi enkmkvdemv tvrditltst cehhfvtidg
      121 katvayipkd sviglskinr ivqffaqrpq vqerltqqil ialqtllgtn nvavsidavh
      181 ycvkargird atsattttsl gglfkssqnt rqeflravrh hn