MULTISPECIES: sensor domain-containing diguanylate cyclase

LOCUS       WP_002911798             323 aa            linear   BCT 23-JUL-2024
            [Enterobacteriaceae].
ACCESSION   WP_002911798
VERSION     WP_002911798.1
KEYWORDS    RefSeq.
SOURCE      Enterobacteriaceae
  ORGANISM  Enterobacteriaceae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales.
REFERENCE   1  (residues 1 to 323)
  AUTHORS   Pei,J. and Grishin,N.V.
  TITLE     GGDEF domain is homologous to adenylyl cyclase
  JOURNAL   Proteins 42 (2), 210-216 (2001)
   PUBMED   11119645
REFERENCE   2  (residues 1 to 323)
  AUTHORS   Aravind,L. and Ponting,C.P.
  TITLE     The GAF domain: an evolutionary link between diverse
            phototransducing proteins
  JOURNAL   Trends Biochem Sci 22 (12), 458-459 (1997)
   PUBMED   9433123
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10482331
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..323
                     /organism="Enterobacteriaceae"
                     /db_xref="taxon:543"
     Protein         1..323
                     /product="sensor domain-containing diguanylate cyclase"
                     /EC_number="2.7.7.65"
                     /GO_function="GO:0005515 - protein binding [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0052621 - diguanylate cyclase activity
                     [Evidence IEA]"
                     /calculated_mol_wt=36160
     Region          28..155
                     /region_name="GAF"
                     /note="GAF domain; pfam01590"
                     /db_xref="CDD:460259"
     Region          167..322
                     /region_name="GGDEF"
                     /note="Diguanylate-cyclase (DGC) or GGDEF domain; cd01949"
                     /db_xref="CDD:143635"
     Site            order(202,245)
                     /site_type="metal-binding"
                     /note="metal binding site [ion binding]"
                     /db_xref="CDD:143635"
     Site            order(207,210..211,215,219,241,243..246)
                     /site_type="active"
                     /db_xref="CDD:143635"
     Site            order(237,265)
                     /site_type="active"
                     /note="I-site [active]"
                     /db_xref="CDD:143635"
ORIGIN      
        1 mklaglhpde qrrlqslrss gllnsgkeer fdrltrlars lynlpvasis lvgedllhik
       61 scagldvdtv prdisfcaht ilqtdplivn dmqqderfhd nplvieapfi rfyagypvql
      121 pdgatvgsfc lmdhqprsfs ahemqilsdl aaivedefkv ldaatsdelt glfnrrgflt
      181 laeyalltaq rrhepvslaf vdldrfkhin dtwgheegdr aliaiadlmk aafresdila
      241 rqggdefiil fantsrhdaa tametlshnv arfnqqaanp wqlafswgcv eydpashpsl
      301 nalvatadrl myqakqkqgr err