MULTISPECIES: pyruvate kinase [Klebsiella].

LOCUS       WP_002911440             480 aa            linear   BCT 19-NOV-2024
ACCESSION   WP_002911440
VERSION     WP_002911440.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 480)
  AUTHORS   Zhong,W., Morgan,H.P., McNae,I.W., Michels,P.A.,
            Fothergill-Gilmore,L.A. and Walkinshaw,M.D.
  TITLE     `In crystallo' substrate binding triggers major domain movements
            and reveals magnesium as a co-activator of Trypanosoma brucei
            pyruvate kinase
  JOURNAL   Acta Crystallogr D Biol Crystallogr 69 (Pt 9), 1768-1779 (2013)
   PUBMED   23999300
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR01064.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     gene            1..480
                     /gene="pyk"
     Protein         1..480
                     /product="pyruvate kinase"
                     /EC_number="2.7.1.40"
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0004743 - pyruvate kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0030955 - potassium ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /calculated_mol_wt=51291
     Region          3..469
                     /region_name="PRK05826"
                     /note="pyruvate kinase; Provisional"
                     /db_xref="CDD:235619"
ORIGIN      
        1 msrrlrrtki vttlgpatdr dnnlekviaa ganvvrmnfs hgtpedhqlr adkvreiaak
       61 lgrhvailgd lqgpkirvst fkegkiflnv gdkflldanl gkgegdkekv gidykglpad
      121 vvpgdillld dgrvqlkvle vqgmkvftev tvggplsnnk ginklgggls aealtdkdka
      181 divtaakigv dylavsfprc gedlnyarrl ardagcdaki vakveraeav cdqdamddvi
      241 lasdvvmvar gdlgveigdp elvgiqkali rrarqlnrsv itatqmmesm itnpmptrae
      301 vmdvanavld gtdavmlsae taagqypset vaamarvclg aekipslnvs khrldvqfdn
      361 veeaiamsam yaanhlkgit aiitmtesgr talmtsriss glpifalsrh ertlnltaly
      421 rgvtpvffds qndgvaaahd avnllrdkgy lvsgdlvvvt qgdvmstigs tnttriltve