MULTISPECIES: bifunctional 4-hydroxy-2-oxoglutarate

LOCUS       WP_002911423             213 aa            linear   BCT 20-NOV-2023
            aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase [Klebsiella].
ACCESSION   WP_002911423
VERSION     WP_002911423.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10792645
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..213
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     Protein         1..213
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /EC_number="4.1.2.14"
                     /EC_number="4.1.3.16"
                     /GO_function="GO:0016830 - carbon-carbon lyase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016833 - oxo-acid-lyase activity
                     [Evidence IEA]"
                     /calculated_mol_wt=22098
     Region          1..213
                     /region_name="PRK05718"
                     /note="keto-hydroxyglutarate-aldolase/keto-deoxy-
                     phosphogluconate aldolase; Provisional"
                     /db_xref="CDD:235577"
     Site            order(45,49,73,134,136,162)
                     /site_type="active"
                     /db_xref="CDD:188632"
     Site            order(49,73,75,94..97,118..121,123,127,136..137,149,
                     153..154)
                     /site_type="other"
                     /note="intersubunit interface [polypeptide binding]"
                     /db_xref="CDD:188632"
     Site            134
                     /site_type="active"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:188632"
ORIGIN      
        1 mknwkttaea iltsgpvvpv ivvkklehav pmakalvagg vrvlevtlrt ecaleairai
       61 akevpdaivg agtvtnveql kavteagaqf aispgltesl lkaatedgti plipgistvs
      121 elmlgmqygl kefkffpaea nggvkalqai agpfghirfc ptggispany rdylalnsvl
      181 ciggswlvpa daleagdydr ittlareave gak