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MULTISPECIES: UTP--glucose-1-phosphate uridylyltransferase GalU


LOCUS       WP_002910105             300 aa            linear   BCT 20-NOV-2023
            [Klebsiella].
ACCESSION   WP_002910105
VERSION     WP_002910105.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 300)
  AUTHORS   Marolda,C.L. and Valvano,M.A.
  TITLE     The GalF protein of Escherichia coli is not a UDP-glucose
            pyrophosphorylase but interacts with the GalU protein possibly to
            regulate cellular levels of UDP-glucose
  JOURNAL   Mol. Microbiol. 22 (5), 827-840 (1996)
   PUBMED   8971705
REFERENCE   2  (residues 1 to 300)
  AUTHORS   Weissborn,A.C., Liu,Q., Rumley,M.K. and Kennedy,E.P.
  TITLE     UTP: alpha-D-glucose-1-phosphate uridylyltransferase of Escherichia
            coli: isolation and DNA sequence of the galU gene and purification
            of the enzyme
  JOURNAL   J. Bacteriol. 176 (9), 2611-2618 (1994)
   PUBMED   8169209
REFERENCE   3  (residues 1 to 300)
  AUTHORS   BERNSTEIN,R.L. and ROBBINS,P.W.
  TITLE     CONTROL ASPECTS OF URIDINE 5'-DIPHOSPHATE GLUCOSE AND THYMIDINE
            5'-DIPHOSPHATE GLUCOSE SYNTHESIS BY MICROBIAL ENZYMES
  JOURNAL   J. Biol. Chem. 240, 391-397 (1965)
   PUBMED   14253441
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF009928.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK13389
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..300
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     gene            1..300
                     /gene="galU"
     Protein         1..300
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /calculated_mol_wt=32490
     Region          1..300
                     /region_name="PRK13389"
                     /note="UTP--glucose-1-phosphate uridylyltransferase GalU"
                     /db_xref="CDD:184021"
     Site            order(14..17,31..32,109,112..115,135,137..138,178..179,
                     201..202,214,242)
                     /site_type="active"
                     /db_xref="CDD:133021"
     Site            order(18,21..25,27..29,33..35,37..39,43,67,69..71,73,
                     77..78,107..108,110,112,177,238,262,268..270,272..274,
                     276..278,281..282)
                     /site_type="active"
                     /note="tetramer interface [active]"
                     /db_xref="CDD:133021"
ORIGIN      
        1 maalnskvrk avipvaglgt rmlpatkaip kemlplvdkp liqyvvneci aagiteivlv
       61 thssknsien hfdtsfelea mlekrvkrql leevqsicpp hvtimqvrqg lakglghavl
      121 cahpvvgdep vavilpdvil deyesdlsrd nlaemisrfd etgasqimve pvedvtaygv
      181 vdckgeslkp gesvpmvgvv ekpkadvaps nlavvgryvl sadiwpllak tppgagdeiq
      241 ltdaidmlie ketveayhmk gkshdcgnkl gymqafveyg irhktlgddf kawletavak