MULTISPECIES: pyruvate kinase PykF [Klebsiella].

LOCUS       WP_002908859             470 aa            linear   BCT 20-NOV-2023
ACCESSION   WP_002908859
VERSION     WP_002908859.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 470)
  AUTHORS   Guerrero-Mendiola,C., Garcia-Trejo,J.J., Encalada,R., Saavedra,E.
            and Ramirez-Silva,L.
  TITLE     The contribution of two isozymes to the pyruvate kinase activity of
            Vibrio cholerae: One K+-dependent constitutively active and another
            K+-independent with essential allosteric activation
  JOURNAL   PLoS ONE 12 (7), e0178673 (2017)
   PUBMED   28686591
  REMARK    Publication Status: Online-Only
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF006664.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK09206
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..470
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     gene            1..470
                     /gene="pykF"
     Protein         1..470
                     /product="pyruvate kinase PykF"
                     /EC_number="2.7.1.40"
                     /GO_function="GO:0004743 - pyruvate kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /calculated_mol_wt=50557
     Region          1..470
                     /region_name="PRK09206"
                     /note="pyruvate kinase PykF"
                     /db_xref="CDD:181699"
     Site            order(3..4,60,62,70..73,158..159,165,168..172,187,195,202,
                     214,250,268..269,273,305,307,336,338..339,389,391,393,404,
                     407..408,410,412..414)
                     /site_type="active"
                     /note="domain interfaces [active]"
                     /db_xref="CDD:238178"
     Site            order(32,34,66,193,220,222,246,278)
                     /site_type="active"
                     /db_xref="CDD:238178"
ORIGIN      
        1 mkktkivcti gpkteseeml tkmleagmnv mrlnfshgdy aehgqriqnl rnvmsktgkk
       61 aailldtkgp eirtiklegg ndvslkagqt ftfttdksvi gnneivavty egftsdlavg
      121 ntvlvddgli gmevtaiegn kvickvlnng dlgenkgvnl pgvsialpal aekdkqdlif
      181 gceqgvdfva asfirkrsdv veirehlkah ggeniqiisk ienqeglnnf deileasdgi
      241 mvargdmgve ipveevifaq kmiiekcira rkvvitatqm ldsmiknprp traeagdvan
      301 aildgtdavm lsgesakgky pleavtimat icertdrvmt srldfnndnr klriteavcr
      361 gavetaekle aplivvatqg gksaravrky fpdatilalt tnettarqlv lskgvvpqlv
      421 eeiastddfy hlgkdlalks glarkgdvvv mvsgalvpsg ttntasvhvl