MULTISPECIES: MFS transporter [Klebsiella].

LOCUS       WP_002907773             388 aa            linear   BCT 28-JUL-2024
ACCESSION   WP_002907773
VERSION     WP_002907773.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 388)
  AUTHORS   Quistgaard,E.M., Low,C., Guettou,F. and Nordlund,P.
  TITLE     Understanding transport by the major facilitator superfamily (MFS):
            structures pave the way
  JOURNAL   Nat Rev Mol Cell Biol 17 (2), 123-132 (2016)
   PUBMED   26758938
REFERENCE   2  (residues 1 to 388)
  AUTHORS   Yan,N.
  TITLE     Structural Biology of the Major Facilitator Superfamily
            Transporters
  JOURNAL   Annu Rev Biophys 44, 257-283 (2015)
   PUBMED   26098515
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 13023516
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..388
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     Protein         1..388
                     /product="MFS transporter"
                     /GO_component="GO:0005886 - plasma membrane [Evidence
                     IEA]"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport
                     [Evidence IEA]"
                     /calculated_mol_wt=39829
     Region          7..374
                     /region_name="MFS_NepI_like"
                     /note="Purine ribonucleoside efflux pump NepI and similar
                     transporters of the Major Facilitator Superfamily;
                     cd17324"
                     /db_xref="CDD:340882"
     Site            order(17..18,21..22,25,57,107..108,110..112,115,135,
                     138..139,142,210,213..214,217..219,222,250,254,303..304,
                     308,312,327,330..331,334..335,338)
                     /site_type="other"
                     /note="putative chemical substrate binding pocket
                     [chemical binding]"
                     /db_xref="CDD:340882"
ORIGIN      
        1 mkinfpllal aigafgigtt efspmgllpv iakgvdvsip vagmlisaya igvmvgaplm
       61 tlllshrarr naliflmgif tvgnllssia pdyttlllsr iitslnhgaf fglgsvvaas
      121 vvpkhkqasa vatmfmglti aniggvpaat wlgetigwrm sflataglgl lamvslwfsl
      181 pkgsagerpd vkkelsvllr pqvlsalltt vlgagamftl ytyispvlnt lthasslfit
      241 amlvligvgf slgnylggkf adrsvsgtlk gfllllmaim laipllaqsq agaaismivw
      301 gaatfavvpp lqmrvmrvah eapglsssvn igafnlgnal gaaaggavis gglgyafvpv
      361 mgaiiaglal llvwfsgraq peeafasq