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MULTISPECIES: LysR family transcriptional regulator [Klebsiella].


LOCUS       WP_002904893             302 aa            linear   BCT 31-DEC-2024
ACCESSION   WP_002904893
VERSION     WP_002904893.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 302)
  AUTHORS   Maddocks,S.E. and Oyston,P.C.F.
  TITLE     Structure and function of the LysR-type transcriptional regulator
            (LTTR) family proteins
  JOURNAL   Microbiology (Reading) 154 (Pt 12), 3609-3623 (2008)
   PUBMED   19047729
REFERENCE   2  (residues 1 to 302)
  AUTHORS   Schell,M.A.
  TITLE     Molecular biology of the LysR family of transcriptional regulators
  JOURNAL   Annu Rev Microbiol 47, 597-626 (1993)
   PUBMED   8257110
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10444115
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..302
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     Protein         1..302
                     /product="LysR family transcriptional regulator"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription
                     factor activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /calculated_mol_wt=33416
     Region          10..67
                     /region_name="HTH_1"
                     /note="Bacterial regulatory helix-turn-helix protein, lysR
                     family; pfam00126"
                     /db_xref="CDD:459683"
     Region          94..294
                     /region_name="PBP2_CrgA_like_5"
                     /note="The C-terminal substrate binding domain of an
                     uncharacterized LysR-type transcriptional regulator
                     CrgA-like, contains the type 2 periplasmic binding fold;
                     cd08474"
                     /db_xref="CDD:176163"
     Site            order(106,110,149,163,166,229,246,273)
                     /site_type="active"
                     /note="putative effector binding pocket [active]"
                     /db_xref="CDD:176163"
     Site            order(107..108,112..113,115..116,119,123,125..131,193,
                     223..227,234..235,238)
                     /site_type="other"
                     /note="putative dimerization interface [polypeptide
                     binding]"
                     /db_xref="CDD:176163"
ORIGIN      
        1 mqisradvad liyfmaiarh rsfsraaiel gvsasalsha lkgletrlgv rllnrttksv
       61 tptaageelv qsvlqpfdti egaleslnry rntptgriri naaveaanll lapvmpafmd
      121 rypdieidiv asnrmvdvtd agfdagiryg gtvpedmvar rlsadirwvi aaspdylery
      181 gtpehpddll hhrcisnrlg ddrvyrwela rdgetyqmtv pgsvtvnhae tglvavlgga
      241 glmyfpeplv apyvkdgrlr lvltewsple egfhiyyssr rqlptglrll iefiqearpl
      301 gl