MULTISPECIES: FAD-dependent urate hydroxylase HpxO [Klebsiella].

LOCUS       WP_002904783             384 aa            linear   BCT 03-JUN-2024
ACCESSION   WP_002904783
VERSION     WP_002904783.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 384)
  AUTHORS   Hicks,K.A., O'Leary,S.E., Begley,T.P. and Ealick,S.E.
  TITLE     Structural and mechanistic studies of HpxO, a novel flavin adenine
            dinucleotide-dependent urate oxidase from Klebsiella pneumoniae
  JOURNAL   Biochemistry 52 (3), 477-487 (2013)
   PUBMED   23259842
REFERENCE   2  (residues 1 to 384)
  AUTHORS   O'Leary,S.E., Hicks,K.A., Ealick,S.E. and Begley,T.P.
  TITLE     Biochemical characterization of the HpxO enzyme from Klebsiella
            pneumoniae, a novel FAD-dependent urate oxidase
  JOURNAL   Biochemistry 48 (14), 3033-3035 (2009)
   PUBMED   19260710
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF033623.1
            Evidence Source    :: NCBIFAM
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..384
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     gene            1..384
                     /gene="hpxO"
     Protein         1..384
                     /product="FAD-dependent urate hydroxylase HpxO"
                     /GO_function="GO:0004846 - urate oxidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /GO_process="GO:0019628 - urate catabolic process
                     [Evidence IEA]"
                     /calculated_mol_wt=41976
     Region          2..382
                     /region_name="urate_HpxO"
                     /note="FAD-dependent urate hydroxylase HpxO; NF033623"
                     /db_xref="CDD:468115"
ORIGIN      
        1 mkaivigagi gglsaavalk qsgidcdvye avkeikpvga aisvwpngvk cmahlgmgdi
       61 metfggplrr mayrdfrsge nmtqfslapl iertgsrpcp vsraelqrem ldywgrdsvq
      121 fgkrvtrcee dadgvtvwft dgssasgdll iaadgshsal rpwvlgftpq rryagyvnwn
      181 glveideala pgdqwttfvg egkrvslmpv sagrfyfffd vplpaglaed rdtlradlsr
      241 yfagwappvq kliaaldpqt tnrieihdie pfsrlvrgrv allgdaghst tpdigqggca
      301 amedavvlga vfrqtrdiaa alreyeaqrc drvrdlvlka rkrcdithgk dmqlteawyq
      361 elreetgeri ingmcdtils gplg