MULTISPECIES: iron-containing alcohol dehydrogenase [Klebsiella].

LOCUS       WP_002904422             382 aa            linear   BCT 08-MAR-2024
ACCESSION   WP_002904422
VERSION     WP_002904422.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 382)
  AUTHORS   Shanbhag,A.P., Ghatak,A. and Rajagopal,S.
  TITLE     Industrial light at the end of the iron-containing (group III)
            alcohol dehydrogenase tunnel
  JOURNAL   Biotechnol Appl Biochem (2022) In press
   PUBMED   35751426
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (residues 1 to 382)
  AUTHORS   Carpenter,E.P., Hawkins,A.R., Frost,J.W. and Brown,K.A.
  TITLE     Structure of dehydroquinate synthase reveals an active site capable
            of multistep catalysis
  JOURNAL   Nature 394 (6690), 299-302 (1998)
   PUBMED   9685163
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10171095
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..382
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     Protein         1..382
                     /product="iron-containing alcohol dehydrogenase"
                     /EC_number="1.1.1.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /calculated_mol_wt=40001
     Region          6..374
                     /region_name="Fe-ADH"
                     /note="iron-containing alcohol dehydrogenases
                     (Fe-ADH)-like; cd08551"
                     /db_xref="CDD:341481"
     Site            order(33,91..93,96,99,132..133,135,154..155,173,181,188,
                     192,257,261,271)
                     /site_type="active"
                     /db_xref="CDD:341481"
     Site            order(188,192,257,271)
                     /site_type="metal-binding"
                     /note="metal binding site [ion binding]"
                     /db_xref="CDD:341481"
ORIGIN      
        1 matihstiis gagassallp llagkssill vtdknvgale atqaihrlla aegrevevid
       61 svpaepnhhd vtqivsqlga sqpqmvvgig ggsvldvakl lsvllhpeap sltsllageq
      121 pqrricslli patagtgsea tpnailaipe qqtkvgiisp vllpdyvall pelttsmpps
      181 iaastgidal chllecftst vanpvsdnaa liglhklvrh iersvnqpqd ltaklemlwa
      241 swyggaainy sgthlvhals yplggtwhlp hgvanailla pcmrvvrpha vakfaqvwdl
      301 ipdadrtlsa eekshalvaw laalvkrlpl pdnlaalgvp qesisalsaa aqnvkrlmnn
      361 apcsvsreei aaiyqtlype ha