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MULTISPECIES: LysR substrate-binding domain-containing protein


LOCUS       WP_002903632             308 aa            linear   BCT 02-MAR-2025
            [Klebsiella].
ACCESSION   WP_002903632
VERSION     WP_002903632.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 308)
  AUTHORS   Tyrrell,R., Verschueren,K.H., Dodson,E.J., Murshudov,G.N., Addy,C.
            and Wilkinson,A.J.
  TITLE     The structure of the cofactor-binding fragment of the LysR family
            member, CysB: a familiar fold with a surprising subunit arrangement
  JOURNAL   Structure 5 (8), 1017-1032 (1997)
   PUBMED   9309218
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF015431.6
            Evidence Source    :: EMBL-EBI
            Source Identifier  :: PF03466.25
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..308
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     Protein         1..308
                     /product="LysR substrate-binding domain-containing
                     protein"
                     /calculated_mol_wt=34519
     Region          11..69
                     /region_name="HTH_1"
                     /note="Bacterial regulatory helix-turn-helix protein, lysR
                     family; pfam00126"
                     /db_xref="CDD:459683"
     Region          100..299
                     /region_name="PBP2_MdcR"
                     /note="The C-terminal substrate-binding domian of
                     LysR-type transcriptional regulator MdcR, which involved
                     in the malonate catabolism contains the type 2 periplasmic
                     binding fold; cd08416"
                     /db_xref="CDD:176108"
     Site            order(115..116,118..119,122,126,128..134,229..234,
                     240..241,243..244)
                     /site_type="other"
                     /note="putative dimerization interface [polypeptide
                     binding]"
                     /db_xref="CDD:176108"
ORIGIN      
        1 mqedinqeit frklsvfmmf makgniarta eamklssvsv hralhtleeg vgcplfvhkg
       61 rnllplqaaw tlleycqdvi slmnrgleat rkvagvgqgr lrigtlyslt letvpriimg
      121 mklrrpelel dltmgsnqml ldmleddald ailiatnege fnntafdvvp lfeddiflaa
      181 paterldasr ladlrdyadr kfvslaegfa tyagfreafh iagfepeivt rvndifsmis
      241 lvqagvgfal lpgrmkkvye kdvqllklae pyqmrqlisi vyshhrerda dllalaaegr
      301 myarsinr