MULTISPECIES: 2-hydroxyacid dehydrogenase [Gammaproteobacteria].

LOCUS       WP_002902515             329 aa            linear   BCT 07-JUN-2024
ACCESSION   WP_002902515
VERSION     WP_002902515.1
KEYWORDS    RefSeq.
SOURCE      Gammaproteobacteria
  ORGANISM  Gammaproteobacteria
            Bacteria; Pseudomonadati; Pseudomonadota.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10187446
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..329
                     /organism="Gammaproteobacteria"
                     /db_xref="taxon:1236"
     Protein         1..329
                     /product="2-hydroxyacid dehydrogenase"
                     /EC_number="1.1.1.28"
                     /GO_function="GO:0008720 - D-lactate dehydrogenase
                     activity [Evidence IEA]"
                     /GO_function="GO:0070404 - NADH binding [Evidence IEA]"
                     /calculated_mol_wt=36233
     Region          1..328
                     /region_name="LDH_like_2"
                     /note="D-Lactate and related Dehydrogenases, NAD-binding
                     and catalytic domains; cd12183"
                     /db_xref="CDD:240659"
     Site            order(76..78,100,234,295,298)
                     /site_type="other"
                     /note="putative ligand binding site [chemical binding]"
                     /db_xref="CDD:240659"
     Site            order(100,105,151,153..156,173..175,204..207,211,214,
                     232..234,258..259,295,297..298)
                     /site_type="other"
                     /note="putative NAD binding site [chemical binding]"
                     /db_xref="CDD:240659"
ORIGIN      
        1 mkiavystkq ydkkylqhvn daygfeleff dflltaktak tangceavci fvnddgsrpv
       61 leelkahgvk yialrcagfn nvdleaakel glrvvrvpay speavaehai gmmmslnrri
      121 hrayqrtrda nfslegltgf tmygktagvi gtgkigvaml rilkgfgmrl lafdpypsaa
      181 alelgveyvd latlykesdv islhcpltde nyhllnreaf dqmkdgvmvi ntsrgalids
      241 qaaidalkhq kigalgldvy enerdlffed ksndviqddv frrlsachnv lftghqaflt
      301 aealisiset tlgnlqqvan getcpnaiv