MULTISPECIES: M20 aminoacylase family protein [Klebsiella].

LOCUS       WP_002901900             389 aa            linear   BCT 20-NOV-2023
ACCESSION   WP_002901900
VERSION     WP_002901900.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 389)
  AUTHORS   Lindner,H.A., Lunin,V.V., Alary,A., Hecker,R., Cygler,M. and
            Menard,R.
  TITLE     Essential roles of zinc ligation and enzyme dimerization for
            catalysis in the aminoacylase-1/M20 family
  JOURNAL   J Biol Chem 278 (45), 44496-44504 (2003)
   PUBMED   12933810
REFERENCE   2  (residues 1 to 389)
  AUTHORS   Rawlings,N.D. and Barrett,A.J.
  TITLE     Evolutionary families of metallopeptidases
  JOURNAL   Methods Enzymol 248, 183-228 (1995)
   PUBMED   7674922
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10145370
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..389
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     Protein         1..389
                     /product="M20 aminoacylase family protein"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_function="GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA]"
                     /calculated_mol_wt=42370
     Region          14..386
                     /region_name="M20_Acy1-like"
                     /note="M20 Peptidase aminoacylase 1 subfamily; cd05666"
                     /db_xref="CDD:349916"
     Site            order(103,105,138,164,362)
                     /site_type="metal-binding"
                     /note="metal binding site [ion binding]"
                     /db_xref="CDD:349916"
     Site            order(187,209..210,214,217,220,237..243,247..248,250,
                     256..258)
                     /site_type="other"
                     /note="putative dimer interface [polypeptide binding]"
                     /db_xref="CDD:349916"
ORIGIN      
        1 mthpllealq vneaqfialr rrfhqqpeig feehqtssev arllgewgye vhrglagtgv
       61 vgtlrvgegk krlglradmd alpmqersgk pwasqvegrf hgcghdghtt tllyaaeyla
      121 rtrqftgtlq lifqpaeell yggrvmvedg lfdqfpcdai fglhnmpgqp lgkiglrdga
      181 mmassdtlhi evkgvgghga vpehtvdatl vachitlalq sivsrnitpf epavvtvgsi
      241 qaghapniin dhvlmkltvr tlneqvretv lqrihdiava qaesfnatat lthvngspvl
      301 rndpatnamv revatalfga eqvgevkpfm gsedfafmle qhphgsyfti gagdepdrcm
      361 vhnpgydfnd allltgaalw cglterylr