MULTISPECIES: NAD(P)-dependent alcohol dehydrogenase [Klebsiella].

LOCUS       WP_002901263             347 aa            linear   BCT 06-MAR-2020
ACCESSION   WP_002901263
VERSION     WP_002901263.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10143035
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..347
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     Protein         1..347
                     /product="NAD(P)-dependent alcohol dehydrogenase"
                     /calculated_mol_wt=37256
     Region          6..345
                     /region_name="sorbitol_DH"
                     /note="Sorbitol dehydrogenase; cd05285"
                     /db_xref="CDD:176188"
     Site            order(39,41,45,51,54,65,114,117,152,269,291..292)
                     /site_type="active"
                     /note="inhibitor binding site [active]"
                     /db_xref="CDD:176188"
     Site            order(39,41,65..66,152)
                     /site_type="other"
                     /note="catalytic Zn binding site [ion binding]"
                     /db_xref="CDD:176188"
     Site            order(95,98,101,109)
                     /site_type="other"
                     /note="structural Zn binding site [ion binding]"
                     /db_xref="CDD:176188"
     Site            order(156,178..180,199..201,205,220,244..245,247,267..269,
                     290..292)
                     /site_type="other"
                     /note="NADP binding site [chemical binding]"
                     /db_xref="CDD:176188"
     Site            order(158,169,171,187,190..192,194,203,219,231,299,
                     302..303,306)
                     /site_type="other"
                     /note="tetramer interface [polypeptide binding]"
                     /db_xref="CDD:176188"
ORIGIN      
        1 mknskailkt pgtmkiiaad ipvpkehevl ikveyvgicg sdvhgfesgp fippkdpnqe
       61 iglghecagt vvavgsrvsk fkpgdrvnie pgvpcghcry clegkynicp dvdfmatqpn
      121 yrgalthylc hpesftyklp dnmgtmegal vepaavgmha amladvkpgk kivilgagci
      181 glmtlqackc lgatdiavvd vlekrlamag klgattving akedtvarcq qfsgdigadi
      241 vfetagsait vkqapylvmr ggkimivgtv pgdsainflk inrevsiqtv fryanrypvt
      301 ieaissgrfd vksmvthiyd yedvqrafde svnnkreiik gvikvnh