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MULTISPECIES: carnitine monooxygenase, oxygenase subunit YeaW


LOCUS       WP_002898571             374 aa            linear   BCT 20-NOV-2023
            [Klebsiella].
ACCESSION   WP_002898571
VERSION     WP_002898571.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 374)
  AUTHORS   Piskol,F., Neubauer,K., Eggers,M., Bode,L.M., Jasper,J.,
            Slusarenko,A., Reijerse,E., Lubitz,W., Jahn,D. and Moser,J.
  TITLE     Two-component carnitine monooxygenase from Escherichia coli:
            functional characterization, inhibition and mutagenesis of the
            molecular interface
  JOURNAL   Biosci Rep 42 (9) (2022)
   PUBMED   36066069
REFERENCE   2  (residues 1 to 374)
  AUTHORS   Kalnins,G., Sevostjanovs,E., Hartmane,D., Grinberga,S. and Tars,K.
  TITLE     CntA oxygenase substrate profile comparison and oxygen dependency
            of TMA production in Providencia rettgeri
  JOURNAL   J Basic Microbiol 58 (1), 52-59 (2018)
   PUBMED   29110324
REFERENCE   3  (residues 1 to 374)
  AUTHORS   Koeth,R.A., Levison,B.S., Culley,M.K., Buffa,J.A., Wang,Z.,
            Gregory,J.C., Org,E., Wu,Y., Li,L., Smith,J.D., Tang,W.H.W.,
            DiDonato,J.A., Lusis,A.J. and Hazen,S.L.
  TITLE     gamma-Butyrobetaine is a proatherogenic intermediate in gut
            microbial metabolism of L-carnitine to TMAO
  JOURNAL   Cell Metab 20 (5), 799-812 (2014)
   PUBMED   25440057
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR007839
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..374
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     gene            1..374
                     /gene="yeaW"
     Protein         1..374
                     /product="carnitine monooxygenase, oxygenase subunit YeaW"
                     /EC_number="1.14.13.239"
                     /calculated_mol_wt=42610
     Region          21..370
                     /region_name="HcaE"
                     /note="Phenylpropionate dioxygenase or related
                     ring-hydroxylating dioxygenase, large terminal subunit
                     [Inorganic ion transport and metabolism, General function
                     prediction only]; COG4638"
                     /db_xref="CDD:443676"
ORIGIN      
        1 msnlspdftl pinfcanpqd awtiparfyt dsqafeheke rifanswicv ahgsevarpn
       61 dyitreiige nivivrgrdn ilrafynvcp hrghqllsge gkaknvitcp yhawafkldg
      121 nlaharncen vanfdsekat lvpvrleeya gfvfinmnpe aesvetqlpg lqdkvleacp
      181 dvhdlklaar fttltpanwk nivdnylecy hcgpahpgfs dsvqvdrywh tmhgkwtlqy
      241 gfakpseqsf kfeegtdaaf hgfwlwpctm fnvtpikgmm tviyefpvde ettlqnydiy
      301 ftneeltddq kaliewyrdv frpedlrlve svqkglksrg yrgqgrimad nsgsgisehg
      361 iahfhnlvaq vfqp