MULTISPECIES: M20 aminoacylase family protein [Klebsiella].

LOCUS       WP_002898215             388 aa            linear   BCT 21-MAR-2023
ACCESSION   WP_002898215
VERSION     WP_002898215.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 388)
  AUTHORS   Lindner,H.A., Lunin,V.V., Alary,A., Hecker,R., Cygler,M. and
            Menard,R.
  TITLE     Essential roles of zinc ligation and enzyme dimerization for
            catalysis in the aminoacylase-1/M20 family
  JOURNAL   J Biol Chem 278 (45), 44496-44504 (2003)
   PUBMED   12933810
REFERENCE   2  (residues 1 to 388)
  AUTHORS   Rawlings,N.D. and Barrett,A.J.
  TITLE     Evolutionary families of metallopeptidases
  JOURNAL   Methods Enzymol 248, 183-228 (1995)
   PUBMED   7674922
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10145370
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..388
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     Protein         1..388
                     /product="M20 aminoacylase family protein"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_function="GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA]"
                     /calculated_mol_wt=42362
     Region          8..383
                     /region_name="M20_Acy1-like"
                     /note="M20 Peptidase aminoacylase 1 subfamily; cd05666"
                     /db_xref="CDD:349916"
     Site            order(97,99,132,158,359)
                     /site_type="metal-binding"
                     /note="metal binding site [ion binding]"
                     /db_xref="CDD:349916"
     Site            order(181,203..204,208,211,214,231..237,241..242,244,
                     250..252)
                     /site_type="other"
                     /note="putative dimer interface [polypeptide binding]"
                     /db_xref="CDD:349916"
ORIGIN      
        1 mnqqqlkqql iawrhylhah pesafeeqnt srfiaeklea mgievhrdig ktgvvgrlkc
       61 gdgkgviair adidaiqlte qgdwsyrsmt aermhgcghd ghtcialgaa qlllqrqnfn
      121 gtvcfvfqpa eepgygaram mddgvierfg ieeiyglhnm pgmkagtiat rvggimased
      181 nfiirikgqg ahaarphmak dplviaaeii lalqtivsrn vdpnvpavis ctelhtdgir
      241 naipthveik gdtrsfapev qmlleermrt iseaicamhg atcqfsythe faptvnwqqc
      301 vdvavtaain vvgaekvngn vaqmmisedf gaflqkipgc fiflgngdss daqgntplhn
      361 acydfndeil ltgaeyfaev vrarlpqe