MULTISPECIES: winged helix-turn-helix domain-containing protein

LOCUS       WP_002898176             409 aa            linear   BCT 21-JAN-2025
            [Klebsiella].
ACCESSION   WP_002898176
VERSION     WP_002898176.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 409)
  AUTHORS   Aravind,L., Anantharaman,V., Balaji,S., Babu,M.M. and Iyer,L.M.
  TITLE     The many faces of the helix-turn-helix domain: transcription
            regulation and beyond
  JOURNAL   FEMS Microbiol Rev 29 (2), 231-262 (2005)
   PUBMED   15808743
REFERENCE   2  (residues 1 to 409)
  AUTHORS   Rosinski,J.A. and Atchley,W.R.
  TITLE     Molecular evolution of helix-turn-helix proteins
  JOURNAL   J Mol Evol 49 (3), 301-309 (1999)
   PUBMED   10473770
REFERENCE   3  (residues 1 to 409)
  AUTHORS   Wintjens,R. and Rooman,M.
  TITLE     Structural classification of HTH DNA-binding domains and
            protein-DNA interaction modes
  JOURNAL   J Mol Biol 262 (2), 294-313 (1996)
   PUBMED   8831795
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10007089
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..409
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     Protein         1..409
                     /product="winged helix-turn-helix domain-containing
                     protein"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /calculated_mol_wt=47308
     Region          1..405
                     /region_name="YcaQ"
                     /note="DNA glycosylase YcaQ, repair of DNA interstrand
                     crosslinks [Replication, recombination and repair];
                     COG3214"
                     /db_xref="CDD:442447"
ORIGIN      
        1 msvlqlslne arhlhlaaqg llkkprrrar pkdilstiqq msllqidtin vvarspylvl
       61 fsrlgsypqh wldeslrnge lmeywaheac flprsdfalv rhrmlnpdnm gwkyhrawme
      121 ehagsiaelv ahigqngpvr sadfthprkg asgwwewkph krhleglfta gevmvverrn
      181 fhrvydltrr vmpdwdderd alsredaeai mlrnsarslg ifraqwlady yrlrqpalpg
      241 llaawqeegl vvpvnvealg emwlhheala qletapggkl tashsavlsp fdpvvwdrkr
      301 aeqlfnfsyr lecytpapkr qygyfvlpll hqgklvgrmd skihrksrel eifalwleeg
      361 vkitrgleqg lrraindfah wqsaerilcr rlpeglfvgq eqgweidad