MULTISPECIES: MFS transporter [Klebsiella].

LOCUS       WP_002895884             433 aa            linear   BCT 01-JAN-2025
ACCESSION   WP_002895884
VERSION     WP_002895884.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 433)
  AUTHORS   Quistgaard,E.M., Low,C., Guettou,F. and Nordlund,P.
  TITLE     Understanding transport by the major facilitator superfamily (MFS):
            structures pave the way
  JOURNAL   Nat Rev Mol Cell Biol 17 (2), 123-132 (2016)
   PUBMED   26758938
REFERENCE   2  (residues 1 to 433)
  AUTHORS   Zhang,X.C., Zhao,Y., Heng,J. and Jiang,D.
  TITLE     Energy coupling mechanisms of MFS transporters
  JOURNAL   Protein Sci 24 (10), 1560-1579 (2015)
   PUBMED   26234418
REFERENCE   3  (residues 1 to 433)
  AUTHORS   Yan,N.
  TITLE     Structural Biology of the Major Facilitator Superfamily
            Transporters
  JOURNAL   Annu Rev Biophys 44, 257-283 (2015)
   PUBMED   26098515
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 13022908
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..433
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     Protein         1..433
                     /product="MFS transporter"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport
                     [Evidence IEA]"
                     /calculated_mol_wt=47409
     Region          22..423
                     /region_name="MFS_ExuT_GudP_like"
                     /note="Hexuronate transporter, Glucarate transporter, and
                     similar transporters of the Major Facilitator Superfamily;
                     cd17319"
                     /db_xref="CDD:340877"
     Site            order(36..37,40..41,44,76,126..127,129..131,134,154,
                     157..158,161,249,252..253,256..258,261,289,293,351..352,
                     356,360,376,379..380,383..384,387)
                     /site_type="other"
                     /note="putative chemical substrate binding pocket
                     [chemical binding]"
                     /db_xref="CDD:340877"
ORIGIN      
        1 msqglnndia vsktrrvvkn lrwwvlvlfl lgvtvnyitr nslgiiapel katlgitteq
       61 yswivgafql aytifqplcg wlidviglkl gfmicatlwa laciahagag swlhlamlrf
      121 fmggaeaaat panaktigew fpkserpiaa gwagvgfsig amlappiiyf ahasfgwqga
      181 fmftgalall wvvlwwafyq tpekhpnlsk seleyikqdn eappvkqpff talktvsknk
      241 rfygiaipaf maepawavls fwvplylake hgmdlkqiam fawlpflaad lgsvvsgylt
      301 rlyvrwfgct rvnsviassv tgaflmlsla lvaitrdpyi tiilisiggf ghqiiscmls
      361 alvvesfdkg qmatvngmrg saawiasflf slligvtadk igfnplfiam gffdligavf
      421 lvafiaerra kra